9 citations
,
November 2024 in “Biotechnology for Sustainable Materials” Keratin-based biomaterials are promising for wound healing, drug delivery, and nerve regeneration due to their biodegradability and biocompatibility.
272 citations
,
September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
175 citations
,
August 1997 in “Nature Genetics” 130 citations
,
April 2003 in “Journal of Investigative Dermatology” Four specific keratins in hair follicles help understand hair structure and function.
130 citations
,
April 2001 in “Journal of Investigative Dermatology” The keratin tail is crucial for skin structure and function.
115 citations
,
August 2014 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Human hair keratin can be used in many medical applications.
97 citations
,
March 2010 in “The American Journal of Human Genetics” A mutation in the KRT74 gene causes tightly curled hair.
84 citations
,
April 2002 in “Archives of Dermatology” Loose anagen hair syndrome may be caused by keratin gene mutations.
71 citations
,
September 2013 in “Materials Science and Engineering C” Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.
68 citations
,
February 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Keratin films from human hair can potentially replace human nail plates for drug testing.
62 citations
,
August 2006 in “Journal of Chromatography B” Modern techniques have improved the understanding of keratin proteins, revealing their roles in various cells and potential in disease diagnosis.
49 citations
,
March 2004 in “Journal of Investigative Dermatology” The hHa7 gene is regulated by androgens in certain body hair, not scalp hair.
35 citations
,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
35 citations
,
April 2008 in “Journal of Biological Chemistry” Hirosaki hairless rats lack hair due to missing DNA with key keratin genes.
35 citations
,
October 2002 in “Biochemical and Biophysical Research Communications” The research cloned keratin 7 genes from humans, mice, and marsupials, found similarities between human and mouse genes, and discovered new areas of K7 expression in mice.
28 citations
,
June 2012 in “International Journal of Molecular Medicine” Radiation damages hair stem cells and changes keratin expression, with Krt5 as a potential marker for radiation effects.
19 citations
,
July 1994 in “Journal of Dermatological Science” Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.
13 citations
,
March 2019 in “Journal of cosmetic dermatology” Heat damages hair, with Asian hair losing more protein than Caucasian hair.
11 citations
,
March 2001 in “Clinics in Dermatology” Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
9 citations
,
June 1959 in “Archives of dermatology” Hair can darken after inflammation and then return to its original color.
1 citations
,
January 2024 in “Scientific reports (Nature Publishing Group)” Human hair was used to make biodegradable plastic films that could be useful for packaging and disposable products.
1 citations
,
February 2023 in “Journal of Natural Fibers” Higher keratin protein levels are important for the wool's shine in Magra sheep.
1 citations
,
January 2013 Depilatories use chemicals to weaken hair for easy removal.
1 citations
,
January 2012 in “Journal of Toxicologic Pathology” A rat had a cyst similar to a hair follicle structure.
July 2023 in “Drug testing and analysis (Print)” Homemade hair treatments can significantly lower drug levels in hair, possibly causing false-negative drug tests.
June 2023 in “Historical records of Australian science/Historical Records of Australian Science” George Ernest Rogers was a notable scientist who made important discoveries about hair and wool proteins.
Keratin peptide signatures in hair may help identify gender and ethnicity.
Keratin peptide signatures in hair may help identify gender and ethnicity.
Keratin peptides in hair may help identify gender and ethnicity, but more research is needed.
48 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.