research Adverse Reactions to Oral Retinoids An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
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research Microneedle-Based Approaches for Skin Disease Treatment
Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
research Endocrine care of transpeople part I. A review of cross-sex hormonal treatments, outcomes and adverse effects in transmen
Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
research A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds
A new wearable LED device helps heal chronic infected wounds at home.
research Control by a hair’s breadth: the role of microRNAs in the skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Psychological interventions in the management of common skin conditions
Using psychological treatments can help manage skin conditions along with regular medical care.
research An overview of JAK/STAT pathways and JAK inhibition in alopecia areata
Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
research Recently Identified Forms of Epidermolysis Bullosa
Three new types of a skin blistering disease were found, caused by specific gene mutations.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications
Adrenal disorders can cause lasting brain and behavior issues in children.
research Side effects of common acne treatments
Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.
research Surrogate end-points or primary outcomes in clinical trials in women with polycystic ovary syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome
The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
research Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease
Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
research Skin disease in pregnancy
Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.
research Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway
Cepharanthine may help treat gastric cancer by causing cancer cell death and affecting energy use.
research Tannic acid modified keratin/sodium alginate/carboxymethyl chitosan biocomposite hydrogels with good mechanical properties and swelling behavior
The hydrogel shows promise for wound healing due to its strong mechanical, antimicrobial, and antioxidant properties.
research Post-finasteride syndrome: An emerging clinical problem
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
research Dermatological manifestations associated with COVID‐19: A comprehensive review of the current knowledge
COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.
research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone
Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
research Interventions for morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
research Nutrition and the deleterious side effects of nutritional supplements
Taking too many vitamin and mineral supplements can cause serious health problems.
research Provision of Patient‐Centered Transgender Care
The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.
research Use of Hair Products Containing Hormone or Placenta by US Military Personnel
About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.
research Improvement in Androgenetic Alopecia (Stage V) Using Topical Minoxidil in a Retinoid Vehicle and Oral Finasteride
Combination therapy improves hair growth in advanced hair loss.
research Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia
Nanotechnology improves minoxidil treatment for hair loss.
research Pediatric Psychocutaneous Disorders
Recognizing and managing skin-related psychiatric disorders in children is crucial for effective treatment.