35 citations
,
April 2008 in “Journal of Biological Chemistry” Hirosaki hairless rats lack hair due to missing DNA with key keratin genes.
86 citations
,
June 1998 in “Journal of Investigative Dermatology” The hairless gene mutation causes baldness by disrupting hair follicle structure.
April 2019 in “Journal of the Endocrine Society” Bilateral ovarian hyperthecosis is a rare but treatable cause of increased facial hair in postmenopausal women.
45 citations
,
August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
19 citations
,
May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications” Reliable method detects finasteride in human plasma at low doses.
A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.
36 citations
,
October 2000 in “British Journal of Dermatology” A different gene near the hairless gene on chromosome 8p21 causes a rare hair loss condition in a German family.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicles repair 3D injuries using a 2D healing process.
December 2023 in “Forensic science international. Genetics” The RapidHIT ID system can effectively get DNA profiles from hair roots with enough cells.
1 citations
,
May 2002 in “British Journal of Dermatology” Hair loss caused by longer latent hair cycle and sudden miniaturization, not gradual follicle size reduction.
18 citations
,
May 2010 in “Zentralblatt für Veterinärmedizin Reihe A” Hair zinc levels don't reliably indicate overall zinc status in animals.
1 citations
,
January 2012 in “Journal of Toxicologic Pathology” A rat had a cyst similar to a hair follicle structure.
29 citations
,
June 2017 in “Journal of Inherited Metabolic Disease” High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
2 citations
,
January 2015 in “Hair transplant forum international” Using human recombinant hyaluronidase in donor strip harvesting may improve the procedure.
11 citations
,
January 2023 in “World Journal of Clinical Cases” Idiopathic hirsutism might not be truly idiopathic but could be an early stage of hyperandrogenic disorders.
June 2014 in “Toxicologie analytique et clinique/Annales de toxicologie analytique” Older age increases positive hair alcohol test results, and chest hair is a good alternative for testing; season affects results, with higher levels in winter.
2 citations
,
August 2024 in “Molecular Genetics & Genomic Medicine” Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.
6 citations
,
June 2016 in “Journal of cellular biochemistry” The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.
October 2025 in “International Wound Journal” Gamma-irradiated amniotic fluid improves healing and reduces thickness of hypertrophic scars.
7 citations
,
April 2022 in “Journal of pharmaceutical and biomedical analysis” The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.
April 2020 in “Journal of the Endocrine Society” Non-classic congenital adrenal hyperplasia (NCCAH) can mimic PCOS and requires genetic testing for proper diagnosis and treatment.
February 2024 in “Malahayati Nursing Journal” High androgen levels can cause hirsutism and increase inflammation.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The model improves understanding of androgen interactions by focusing on signal intensity and system capacity.
December 2022 in “Biochemical and Biophysical Research Communications” HtrA2 activity is crucial for normal hair growth by regulating fat cell development.
September 2010 in “대한화장품학회지(J. Soc. Cosmet. Scientists Korea)” The study developed a reliable method to measure active ingredients in hair nourisher products using HPLC.
7 citations
,
January 2002 in “Biological Trace Element Research” Children with pituitary dwarfism have higher zinc and copper, lower manganese, and similar iron levels in hair compared to normal children.
May 2009 in “OPAL (Open@LaTrobe) (La Trobe University)” Suppressing the HGPS mutation may improve symptoms and suggest reversibility.
20 citations
,
December 1999 in “Journal of Investigative Dermatology” Mutations in the hHb6 gene cause the hair disorder monilethrix.
Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.
4 citations
,
June 2017 in “Anais Brasileiros De Dermatologia” Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.