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Severe CCCA may be biologically and clinically different from milder forms.

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

Improving CRISPR/Cas systems can make gene editing more efficient and precise.

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

LH and hCG reduce certain protein levels in women's skin.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.

Inhibiting class I HDACs helps maintain hair growth ability in skin cells.

Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.

Hoxd gene regulation in mammals and birds is robust despite differences in DNA sequences, due to 3D chromatin structures.

Congenital atrichia with papular lesions is often misdiagnosed, and new diagnostic criteria can improve accuracy.

Hair cortisol may help identify adrenal insufficiency in sickle cell disease patients.

The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.

New genetic mutations linked to rare skin disorders were found in three newborns.

μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.

Certain immune system genes are linked to a higher risk of psoriasis and psoriatic arthritis, while others may offer protection.

Vitamin D receptor is crucial for starting hair growth after birth.

Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.

Hutchinson-Gilford Progeria Syndrome caused rapid aging due to a genetic mutation, with treatments to manage symptoms.

The first Japanese case of a genetic hair disorder caused by specific mutations in the LIPH gene was identified.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.

Fixing DNA errors is crucial to prevent skin cancer.

Gene therapy with a vitamin D receptor gene improved hair growth in rats with a type of rickets-related baldness.

A rare gene variant causes sexual development issues in siblings, needing personalized treatment.

Disrupting the Hars2 gene in mice causes hearing loss due to mitochondrial problems and hair cell damage.

A new mutation in the FLCN gene linked to Birt-Hogg-Dube syndrome was found, suggesting people with certain lung collapse should be tested for this mutation and screened for kidney and colon cancer.