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A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.

ELIP-based CRISPR delivery improves heart disease gene editing but needs more testing.

The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Genetic mutations linked to ectodermal dysplasias and hair loss were identified in Pakistani families.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

HLA can be linked to autoimmune hepatitis.

A new gene mutation causes complete androgen insensitivity in a 16-year-old with a female appearance.

Key genes linked to hair growth and cancer were identified in hairless mice.

Blocking the CCR5 receptor may be a new way to treat hair loss from alopecia areata.

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

Genetically modified rats help reveal how vitamin D affects bone and skin health.

The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.

Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Early recognition of skin lesions in Birt-Hogg-Dubé syndrome is crucial for detecting renal tumors early.

A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.

Genetic testing can diagnose hair loss linked to DSG4 gene variants.

Certain genes help dermal papillae cells in hair follicles grow and group together.

A new protein, mK6irs, is found in specific hair layers and may help understand hair growth and diseases.

Modified β-catenin causes different effects in hair and skin cells, leading to cysts or tumors.

Sea cucumbers have unique genes that help them regenerate their intestines.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.

Activating Kras in mouse skin causes excess skin and hair loss.

Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.