January 2023 in “Marmara University Open Access System” Tideglusib with hydrogel improves wound healing in rats.
April 2017 in “Journal of Investigative Dermatology” Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
68 citations
,
March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
556 citations
,
September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
211 citations
,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
150 citations
,
June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
70 citations
,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
58 citations
,
January 2020 in “International Journal of Molecular Sciences” Different methods of preparing Platelet-Rich Plasma (PRP) can affect wound healing and hair regrowth in plastic surgery. Using a kit with specific standards helps isolate PRP that meets quality criteria. Non-Activated PRP and Activated PRP have varying effects depending on the tissue and condition treated. For hair regrowth, Non-Activated PRP increased hair density more than Activated PRP. Both treatments improved various aspects of scalp health.
56 citations
,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
56 citations
,
February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
39 citations
,
July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
37 citations
,
December 2024 in “Theranostics” The hydrogel effectively treats infected burn wounds by reducing pain and preventing infection.
23 citations
,
September 2018 in “Journal of Investigative Dermatology” A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.
13 citations
,
March 2022 in “Cell Death and Differentiation” Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
10 citations
,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
9 citations
,
April 2025 in “International Journal of Nanomedicine” An injectable ibuprofen gel speeds up diabetic wound healing by reducing inflammation and promoting tissue growth.
9 citations
,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
6 citations
,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
4 citations
,
February 2017 in “Journal of Cutaneous Medicine and Surgery” Compounds from certain trees used by First Nations people show potential for treating skin conditions and promoting hair growth, but more research is needed to confirm their safety and effectiveness.
3 citations
,
April 2022 in “Veterinary world/Veterinary World” The mesenchymal stem cell-conditioned medium gel improved burn healing and hair growth in rats better than other treatments.
3 citations
,
December 2019 in “Journal of Cosmetic and Laser Therapy” PRGF treatments increased hair number and thickness in people with hair loss, with more injections leading to better results.
1 citations
,
January 2018 in “Recent clinical techniques, results, and research in wounds” Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
March 2026 in “Journal of South Asian Federation of Obstetrics and Gynaecology” Using platelet-rich plasma during cesarean delivery improves wound healing and reduces infections.
Plasma-activated water heals diabetic wounds better than other treatments.
January 2026 in “Frontiers in Materials” Metal-organic frameworks help heal wounds by effectively delivering medicine.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
280 citations
,
July 2018 in “Antioxidants” Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
23 citations
,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
January 2026 in “International Journal of Applied Pharmaceutics” A 10% MSC secretome hair tonic best promotes hair growth in alopecia.