37 citations
,
October 2009 in “Veterinary Dermatology” Canine hair follicles contain stem-like cells with high growth potential.
12 citations
,
May 2016 in “Experimental Dermatology” A new skin model from hair follicles is a safer, simpler alternative for skin tests.
441 citations
,
May 1996 in “Journal of Cell Science” Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.
March 2026 in “Experimental Dermatology” The new model helps understand and develop treatments for genetic skin disorders like AEC.
April 2026 in “Research Square” 13 citations
,
November 2003 in “Humana Press eBooks” ES cells can be turned into hair follicle cells in a lab setting.
January 2007 in “Zhonghua shiyan waike zazhi” Basal layer skin cells help form the epidermis and hair follicles.
2 citations
,
September 2020 in “Biomedical materials” Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
A new hydrogel made from human hair keratin can help regenerate skin and fight bacteria.
25 citations
,
July 1994 in “Journal of Cell Science” Immortalized rat dermal papilla cells can still induce hair growth.
October 2021 in “Journal of Investigative Dermatology” The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
22 citations
,
January 2017 in “Advanced Healthcare Materials” The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Human umbilical cord stem cell exosomes may help treat hair loss by promoting hair cell growth.
April 2023 in “Journal of Investigative Dermatology” Transplanted stem cells from hair follicles significantly boosted hair growth and normalized follicles in certain mice.
4 citations
,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
9 citations
,
July 2008 in “Oncology Reports” HPV16-transformed cells can change human skin cell properties, aiding tumor growth.
April 2018 in “Journal of Investigative Dermatology” IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
Researchers developed a cost-effective, ethical skin model using hairless guinea pig cells for toxicology studies.
120 citations
,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
22 citations
,
May 2011 in “Molecular Biology of the Cell” Integrin-linked kinase is crucial for normal skin healing.
7 citations
,
July 2018 in “Stem cell research” Hair samples can be used to create stem cells easily and non-invasively.
20 citations
,
November 2003 in “American Journal Of Pathology” Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
1 citations
,
January 2009 in “Journal of Dermatology and Venereology” Cells from the upper hair follicle grow more actively, suggesting stem cells may be located there.
21 citations
,
December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
6 citations
,
January 1990 in “The Journal of Dermatology” Human hair follicle cells can be grown successfully on floating collagen membranes without extra support.
August 2005 in “The Journal of Cell Biology” Sgk3 kinase is essential for normal hair growth in mice.
18 citations
,
July 2023 in “International Journal of Molecular Sciences” KY19382 speeds up wound healing by activating a specific cell signaling pathway.
52 citations
,
February 1986 in “Journal of Histochemistry & Cytochemistry” Some hair proteins are specific to hair, while others are also found in skin cells.
January 2006 in “Zhongguo bijiao yixue zazhi” A new method efficiently isolates and cultures rat hair follicle cells.
24 citations
,
April 2017 in “Oncology Reports” The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.