research Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome
Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
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120-150 / 1000+ resultsresearch Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch
ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.
research Thymic stromal lymphopoietin controls hair growth
Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Low fucosylation defines the glycocalyx of progenitor cells and melanocytes in the human limbal stem cell niche
Low fucosylation boosts stem cell growth in the eye.
research Biochemistry of Vitamin B: Metabolic Regulations, Deficiency Disorders and Emerging Therapeutic Strategies
Vitamin B is essential for metabolism and health, and new therapies are improving its effectiveness.
research Stem Cell Use to Treat Dermatological Disorders
Stem cell therapy shows promise for treating skin disorders.
research Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo
ING5 is crucial for stem cell maintenance and preventing certain cancers.
research Stem-cell therapy in dermatology – Challenges and opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
research Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro
Wharton's jelly stem cells show diverse traits and functions.
research Platelet-derived bio-products: Classification update, applications, concerns and new perspectives
Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
research Tailored chromatin modulation to promote tissue regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration
Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
research Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium
FoxN1 gene is essential for proper thymus structure and preventing hair loss.
research Industry Report
The regenerative medicine industry saw business growth with new partnerships, clinical trials, and financial investments.
research Epidermal stem cells: practical perspectives and potential uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Poster 148 Severe Hair Loss during Inpatient Rehabilitation due to Telogen Effluvium: A Case Report
A woman had temporary hair loss due to stress from a spinal cord injury.
research Poster 150 Rehabilitating the Journal Club: A Review of Journal Clubs in Physical Medicine and Rehabilitation
The document concludes that severe trauma can cause temporary hair loss, known as Telogen Effluvium, which usually resolves without treatment.
research 918 Skin morphogenesis by coupling biochemical-bioelectric signals: Calcium oscillations coordinate dermal cell movement by epidermis-derived SHH signaling during feather bud orientation
Calcium signals and SHH guide the direction of feather growth in chicken skin.
research 916 Gynecologic and hormonal comorbidities of scarring alopecia: A retrospective review
Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.
research Long-term renewal of hair follicles from clonogenic multipotent stem cells
Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
research Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research Signaling in the stem cell niche: regulating cell fate, function and plasticity
The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
research The Senescence–Stemness Alliance – A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
research CD34 glycoprotein identifies putative stem cells located in the isthmic region of canine hair follicles
CD34 marks potential stem cells in dog hair follicles.
research Label Retention Identifies a Multipotent Mesenchymal Stem Cell-Like Population in the Postnatal Thymus
The postnatal thymus has cells like mesenchymal stem cells that can become different cell types and help maintain thymus structure.
research Epidermal stem cell fate: what can we learn from embryonic stem cells?
Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.