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Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.

The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.

Betulinic acid can help treat hepatitis C by stopping virus replication.

Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.

Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.

As of 1994, treatments for liver cancer had not significantly improved patient survival.

Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.

Two genetic disorders affect biotin metabolism, causing severe skin, hair, and metabolic issues.

Methadone may worsen liver fibrosis in males with HCV.

Ethylenthiourea is toxic to the liver and nervous system, especially with alcohol.

Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.

Croton membranaceus root extract can change how drugs are processed in the body.

The document describes a way to measure biotin in blood to prevent wrong test results in hormone level testing.

Coal tar shampoo increases enzyme activity in hair follicles, enhancing carcinogen binding to DNA.

Early diagnosis and treatment of biotinidase deficiency are crucial to prevent vision problems.

Hepatitis B virus alters steroid hormones in male mice, reducing dihydrotestosterone to inhibit viral replication.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

Valproic acid does not change biotinidase enzyme activity in children's blood.

Skin enzymes convert topical drugs into active forms, affecting drug effectiveness and safety.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Long-term use of hormonal contraceptives may harm liver function.

Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.

Budesonide alone is less effective than standard treatment for autoimmune hepatitis.

Early detection and biotin treatment improve outcomes for biotinidase deficiency.