research The Use of Finasteride in Treating Androgenetic Alopecia in Adult Men
Finasteride effectively treats mild to moderate hair loss in men aged 18-41, with some side effects.
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research Study on Autoimmune Thyroid Disorders in Chronic Spontaneous Urticaria at a Tertiary Care Central Rural Hospital in India
People with chronic hives should be tested for thyroid autoimmunity to manage their condition better.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables
Mutant mice help researchers understand hair growth and related genetic factors.
research Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure
Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
research Sulfatase inhibitors: a patent review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Acquired scalp alopecia. Part I: A review
Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
research Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture
Autophagy is important for human hair growth and health.
research Androgens Affect the Activity of Human Sebocytes in Culture in a Manner Dependent on the Localization of the Sebaceous Glands and Their Effect Is Antagonized by Spironolactone
Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
research Polycystic Ovarian Syndrome: Long-Term Health Consequences
Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.
research Genetic Hair Disorders: A Review
The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.
research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
research Dermatological Manifestations of Stress in Normal and Psychiatric Populations
Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.
research Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Skin diseases in consequence of endocrine alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
research Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice
Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.
research The Role of Cytochrome P-450 in Dermatology
Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
research Keratin function and regulation in tissue homeostasis and pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Ophthalmic manifestations of Demodex spp. infection – what should a dermatologist know?
Demodex mites can cause eye problems like itching, dry eyes, and styes.
research Intractable Diffuse Alopecia Caused by Multifactorial Side-Effects in Treatment of Acute Lymphocytic Leukemia: Connection to Iatrogenic Failure of Estrogen Secretion
The patient's long-term hair loss was caused by leukemia treatments and low estrogen levels, worsened by her genetic tendency for hair loss.
research Androgen excess disorders remain undiagnosed in one of every four premenopausal women with Type 1 diabetes
25% of premenopausal women with Type 1 diabetes have undiagnosed androgen excess disorders.
research Clinical Management in Psychodermatology
The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.
research Scalp biopsy identifies systemic amyloidosis presenting as isolated telogen effluvium: A case report
A scalp biopsy revealed systemic amyloidosis in a woman who initially seemed to have a common hair loss condition.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Androgens and Female Sexual Function and Dysfunction—Findings From the Fourth International Consultation of Sexual Medicine
Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
research Androgens in women
Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
research The Safety of Testosterone Therapy in Women
Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone therapy is effective and safe for women with low sexual desire, but it's hard to access.
research Malassezia and the Asian menopausal skin
Menopause-related skin changes may increase fungal infections and inflammation.