MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
October 2023 in “Benha Journal of Applied Sciences” Insulin resistance may contribute to hair loss in people with androgenic alopecia.
July 2025 in “International Journal of Dermatology”
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.
November 2025 in “Mendeley Data” JAK inhibitors can be safely used for alopecia areata in patients with latent hepatitis B or stable tuberculosis with proper monitoring.
September 2018 in “Fertility and Sterility” The HSD3B1 variant increases hair loss risk in overweight women with PCOS.
4 citations
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January 2009 in “Indian Journal of Dermatology, Venereology and Leprology” A patient with granuloma annulare experienced both isotopic and isomorphic responses, with skin lesions responding to steroids but relapsing after stopping treatment.
April 2019 in “Journal of the Endocrine Society” An over-the-counter vitamin/mineral supplement improved hair loss and blood sugar control in a woman with non-classic 11-hydroxylase deficiency.
June 2014 in “Toxicologie analytique et clinique/Annales de toxicologie analytique” Older age increases positive hair alcohol test results, and chest hair is a good alternative for testing; season affects results, with higher levels in winter.
9 citations
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December 1987 in “Archives of Dermatology” Two genetic disorders affect biotin metabolism, causing severe skin, hair, and metabolic issues.
39 citations
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August 2001 in “Clinical endocrinology” Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.
53 citations
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June 2012 in “Annales d'Endocrinologie” The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
37 citations
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January 2010 in “Internal Medicine” A woman's liver was damaged by taking the herbal supplement Shou-Wu-Pian, but it got better after she stopped using it.
1 citations
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September 2018 in “Australasian Journal of Dermatology” A boy with GAPO syndrome had hair loss similar to male pattern baldness without hormone issues, possibly due to skin or blood vessel problems.
26 citations
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August 2004 in “Alcoholism Clinical and Experimental Research” Ethanol-induced motor incoordination in rats is not affected by increased neuroactive steroids.
110 citations
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January 1995 in “European Journal of Neuroscience” Glycine is a key transmitter in rat spinal cord synapses, often alongside GABA.
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August 2022 in “JAAD case reports” Pioglitazone use was linked to hair regrowth in a patient with permanent hair loss from cicatricial alopecia.
81 citations
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July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
12 citations
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September 1990 in “The Anatomical Record” Human anagen hair follicles have unique carbohydrate patterns during keratinization.
27 citations
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August 2010 in “Clinics in Dermatology” Hepatitis C virus can cause skin diseases and dermatologists play a crucial role in identifying these conditions.
1 citations
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November 2025 in “Neuro-Oncology” Safusidenib erbumine shows promise as a treatment for certain brain tumors, but mild side effects like hair loss need attention.
18 citations
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August 2012 in “Cutaneous and Ocular Toxicology” People with alopecia areata have higher insulin resistance.
26 citations
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March 2006 in “Endocrine, metabolic & immune disorders. Drug targets” This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.
44 citations
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July 1993 in “Journal of Investigative Dermatology”
April 2025 in “Antioxidants” Rhus semialata gall extract and Penta-O-Galloyl-β-D-Glucose may effectively reduce hair loss.
6 citations
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October 2016 in “Journal of Chemotherapy” A man lost all his hair as a rare side effect after hepatitis C treatment.
January 2021 in “대한피부과학회지” The solution increased hair density safely and effectively for hair loss.
38 citations
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March 2010 in “Medicine” Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.
13 citations
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January 1997 in “Biochemical Pharmacology” Human liver enzyme DHEA ST helps process minoxidil.
October 2004 in “Australian Prescriber” Agalsidase alfa helps treat Fabry's disease but needs more research for long-term benefits.