103 citations
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June 2018 in “International Journal of Molecular Sciences” FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
94 citations
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
81 citations
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May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
75 citations
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November 2016 in “Medicines” Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
73 citations
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June 2010 in “PLoS Genetics” A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
69 citations
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February 2021 in “PLoS Computational Biology” Securinine and ajmaline may effectively treat liver cancer, with securinine being less toxic to normal cells.
68 citations
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November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
67 citations
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February 2020 in “Journal of Ginseng Research” Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.
67 citations
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February 2015 in “Life Sciences” Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.
55 citations
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November 2004 in “Expert opinion on drug safety” Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.
49 citations
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October 2014 in “International Scholarly Research Notices” Eclipta alba has many health benefits and contains compounds with potential for drug development.
47 citations
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March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
46 citations
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August 2019 in “Journal of Ethnopharmacology” Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
45 citations
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January 2020 in “Pharmaceutical Biology” Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.
42 citations
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May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
39 citations
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September 2016 in “Expert Opinion on Drug Delivery” New drug delivery methods can make natural compounds more effective and stable.
35 citations
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October 2017 in “Trends in Molecular Medicine” Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
33 citations
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January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
32 citations
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April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
32 citations
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December 2014 in “Cold Spring Harbor Perspectives in Medicine” Disruptions in epidermal polarity genes can lead to skin diseases.
29 citations
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September 2024 in “AAPS PharmSciTech” Transcutol® helps drugs penetrate the skin more effectively in various formulations.
28 citations
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September 2013 in “Expert Opinion on Therapeutic Patents” New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
27 citations
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June 2015 in “Revista Brasileira de Farmacognosia” Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.
26 citations
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November 2016 in “European Journal of Clinical Pharmacology” Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.
26 citations
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May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
25 citations
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January 2019 in “Annals of Dermatology” Blocking the NOTCH pathway can prevent fibrosis in systemic sclerosis.
24 citations
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December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
23 citations
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January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.