Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
136 citations
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April 2010 in “British Journal of Dermatology” Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.
15 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
11 citations
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January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.
6 citations
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September 2012 in “Our Dermatology Online” Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
3 citations
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December 2022 in “Cells” Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
2 citations
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November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
2 citations
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September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
March 2022 in “International Journal of Trichology” Smoking may worsen hair loss, but more research is needed.
1 citations
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April 2025 in “Phycology” Phlorotannins from brown seaweeds may improve skin and hair health in cosmetics.
September 2023 in “Cureus” Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
72 citations
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March 2005 in “British Journal of Dermatology” AGA can occur in children with family history; early diagnosis and treatment important.
December 2017 in “Revista Brasileira de Saúde Materno Infantil” Pregnant women with Systemic Lupus Erythematosus have a higher risk of blood clotting problems.
8 citations
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October 1988 in “Clinics in dermatology” The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.
October 2022 in “Medičnì perspektivi” Darier-White disease causes skin and nail issues, starts around age 20, worsens until 40-50, and has poor treatment options.
February 2025 in “East African Scholars Journal of Medical Sciences” Higher testosterone and DHEA-S levels may be linked to male pattern baldness.
Continuous treatment is essential to manage male pattern baldness effectively.
7 citations
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March 2025 in “Archives of Dermatological Research” Trichoscopy helps better understand and manage alopecia areata, improving patient outcomes.
26 citations
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March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
85 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
6 citations
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February 2004 in “Clinical and Experimental Ophthalmology” The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.
November 2013 in “John Wiley & Sons, Ltd eBooks” Skin symptoms can indicate endocrine disorders and have various treatments.
March 2025 in “Archives of Dermatological Research” Early-onset hair loss in Egyptian males is linked to genetics, hormones, and lifestyle factors like smoking and diet.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” Genetic risk for hair loss can increase depression risk, but depression doesn't increase hair loss risk.
June 2024 in “Skin Research and Technology” Botulinum toxin treatment improves hair follicle width and length in androgenetic alopecia.
141 citations
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November 2007 in “Journal of Investigative Dermatology” Balding cells age faster due to stress, suggesting stress-targeting treatments for hair loss.
AI can predict hair loss patterns to improve care and treatment.
September 2019 in “Zagazig university medical journal” PRP injections can help reduce hair loss in some people with Androgenetic Alopecia.
13 citations
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January 2019 in “Indian Journal of Dermatology” Men with early-onset hair loss have more heart disease risk factors.