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Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Compound 1 showed promising anticancer activity.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

2,5-DBH shows promise for improving drugs in cancer, brain disorders, and infections.

The compound 4c showed strong potential as an anticancer agent.

Polyamines help fix DNA damage accurately in cells.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.

Polyamines help repair DNA breaks and may influence cancer development.

A new method using solid-state circular dichroism anisotropy can distinguish similar chiral compounds better than traditional techniques.

Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

New retinoids are effective for various skin conditions and are being developed to have fewer side effects.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Compound 15a was effective in inhibiting 5α-reductase.

N‐AOHPA is a promising alternative to traditional surfactants for better hair conditioning.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

A new method effectively predicts estrogen-related health effects for early screening.