176 citations
,
February 2006 in “Cancer Research” Patched1 helps prevent tumors by controlling cell growth.
October 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Researchers developed a method to label and study human hair follicle stem cells using a fluorescent protein.
October 2021 in “Journal of Investigative Dermatology” DPP4, a molecule in skin, helps heal large wounds and regrow hair follicles when its levels are reduced.
Fgf20 is crucial for hair follicle formation by influencing cell movement and growth.
8 citations
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April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
5 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
2 citations
,
February 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Transplanting a mix of specific skin cells can significantly improve the repair of damaged hair follicles.
January 2006 in “Chinese Journal of Dermatology” Mesenchymal cells are essential for hair follicle stem cell growth.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
7 citations
,
February 2025 in “Stem Cell Research & Therapy” Human hair follicle stem cells improve ovarian function in mice with damaged ovaries.
Dermal papilla cells can help form hair-like structures in lab-grown skin cells.
5 citations
,
July 2022 in “Genes” Increasing EGR1 levels makes hair root cells grow faster.
3 citations
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July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model” Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.
75 citations
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October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
April 2018 in “Journal of Investigative Dermatology” Fat under the skin can help hair grow longer, darker, and increase cell growth.
211 citations
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April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.
3 citations
,
September 2024 in “Journal of Microbiology and Biotechnology” Human placenta extract reduces inflammation and symptoms in atopic dermatitis.
8 citations
,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
10 citations
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August 2023 in “The EMBO Journal” Kdm6b is crucial for skin cell differentiation.
April 2018 in “Journal of Investigative Dermatology” Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.
September 2025 in “Digital Commons - RU (Rockefeller University)” Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.
90 citations
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
January 2024 in “Biomaterials Research” 3D-cultured cells in HGC-coated environments improve hair growth and skin integration.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Damaged hair follicle stem cells may leave the skin to help maintain youthfulness.
25 citations
,
July 2008 in “British Journal of Dermatology” CD10 and CD34 levels change during hair development and different hair growth stages, which could be important for hair regeneration treatments.
3 citations
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December 2024 in “Stem Cell Reports” Low fucosylation boosts stem cell growth in the eye.
109 citations
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April 1998 in “Journal of Investigative Dermatology” HGF/SF injections can stimulate hair growth and increase hair follicle size in mice.
22 citations
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July 2015 in “PloS one” Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
June 2026 in “Scientific Reports” Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.