46 citations
,
August 2006 in “PubMed” A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.
3 citations
,
June 2000 in “Journal of The American Academy of Dermatology” Men with balding at age 45 had higher IGF-1 and lower IGFBP-3 levels, suggesting these factors might influence male pattern baldness.
February 2026 in “Mendeley Data” Early hair loss may indicate higher risk of diabetes and heart disease.
July 2021 in “International Journal of Community Medicine and Public Health” Men with type 2 diabetes often have low testosterone and signs of hypogonadism, especially if they are overweight.
4 citations
,
December 1989 in “The Journal of Dermatology” Human hair proteins have similar cysteine and glycine levels to skin proteins.
2 citations
,
September 2017 in “Plastic and Aesthetic Research” Healthy Han Chinese have lower hair density than whites and Africans, and transplanting 300 hair units can nearly restore normal hair density.
February 2026 in “Applied immunohistochemistry & molecular morphology” CD34+ cells decrease in bald areas, while Sox9 stays high, suggesting hair loss in AGA is linked to stem cell issues.
14 citations
,
September 2018 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
July 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” Scalp tissue micrografts can effectively treat hair loss by increasing hair density and thickness.
19 citations
,
August 1999 in “European journal of endocrinology” The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
42 citations
,
April 2009 in “Human Genetics” A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.
January 2023 in “International journal of dermatology, venereology and leprosy sciences” People with alopecia areata have different blood markers that suggest inflammation and immune system issues compared to healthy individuals.
3 citations
,
February 2011 in “Journal of Biomedical Research/Journal of biomedical research” A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.
1 citations
,
September 2023 in “Acta dermato-venereologica” Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.
July 2013 in “The Journal of Clinical Endocrinology & Metabolism” People with moderate or severe hair loss have higher death rates from diabetes and heart disease.
2 citations
,
January 2005 Men with a certain type of hair loss (vertex type AGA) may have higher levels of bad fats (triglycerides) and lower levels of good cholesterol (HDL), suggesting they could be at risk for high fat levels in the blood (hyperlipidemia).
February 2026 in “Mendeley Data” Early hair loss may indicate higher risk of diabetes and heart disease.
January 2025 in “Mansoura Medical Journal” Serum IMA levels don't help diagnose AGA but may indicate its severity.
1 citations
,
September 1986 in “Journal of the Forensic Science Society” Hair root sheaths can be used to accurately analyze genetic markers.
October 2022 in “Benha Journal of Applied Sciences” Human Beta Defensin 1 levels do not predict the risk or severity of Alopecia Areata.
3 citations
,
April 2020 in “American Journal of Case Reports” A new mutation in the HJV gene was found in a young woman with juvenile hemochromatosis, causing unusual symptoms like secondary hypothyroidism.
20 citations
,
December 2019 in “International Journal of Molecular Sciences” HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.
5 citations
,
March 2020 in “Aids Reviews” Hair antiretroviral concentration is affected by hair type, segment position, housing, drug use, sexual behavior, kidney function, and genetics.
February 2010 in “Journal of The American Academy of Dermatology” Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.
16 citations
,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Blocking interferon-gamma helps prevent and treat hair loss in Alopecia Areata.
July 2025 in “Journal of the American Academy of Dermatology” Hair diameter diversity helps assess hair loss, but its standard measure varies by individual and ethnicity.
55 citations
,
July 1997 in “Clinical Endocrinology” Growth hormone therapy boosts androgen effects on skin in men.
46 citations
,
May 1997 in “British journal of dermatology/British journal of dermatology, Supplement” Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.
August 2025 in “Intisari Sains Medis” The buffy coat method yields higher TGF-β1 levels in PRP, especially in males.
22 citations
,
August 2016 in “European Eating Disorders Review” Adolescent girls with anorexia nervosa have lower hair cortisol levels than healthy and psychiatric peers.