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research Dermal Hedgehog Signaling in Papillary Fibroblasts: An Emerging Key Player in Skin Regeneration

2 citations , January 2022 in “Journal of Investigative Dermatology”

Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.

research The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation

166 citations , July 1999 in “American Journal Of Pathology”

The hairless (hr) gene is essential for normal hair follicle function and its mutation leads to hair loss.

research TGF‐β and HSP70 profiles during transformation of yak hair follicles from the anagen to catagen stage

10 citations , February 2019 in “Journal of cellular physiology”

TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.

research Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration

3 citations , September 2021 in “Journal of Clinical Medicine”

Epidermal signaling helps regenerate fingertip tissue.

research Overexpression of mIGF-1 in Keratinocytes Improves Wound Healing and Accelerates Hair Follicle Formation and Cycling in Mice

55 citations , October 2008 in “American Journal Of Pathology”

mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.

research [The effect of cgVEGF164 on the growth of murine hair follicles].

1 citations , January 2019 in “PubMed”

cgVEGF164 boosts hair follicle growth in mice.

research Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome

2 citations , February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.

research An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis

99 citations , September 2004 in “Development”

Proper hedgehog signaling is crucial for maintaining healthy skin stem cells.

research Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog

231 citations , October 1999 in “Journal of Clinical Investigation”

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

research Gene expression profiling gets to the root of human hair follicle stem cells

92 citations , December 2005 in “The Journal of clinical investigation/The journal of clinical investigation”

Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.

research Histidine decarboxylase expression influences the neofolliculogenesis of newborn mouse dermal cells

2 citations , June 2012 in “Journal of Dermatological Science”

The gene HDC is important for the development of hair follicles in newborn mice.

research Cooperation of TGF‐β and FGF signalling pathways in skin development

23 citations , May 2023 in “Cell Proliferation”

TGF-β and FGF pathways are crucial for skin development and regeneration.

research Hair Follicle Pluripotent Stem (hfPS) Cells

2 citations , January 2009 in “Human cell culture”

research FGF18 signaling determines radioresistance of telogen hair follicles by the arrest of hair cycling

September 2016 in “Journal of dermatological science”

FGF18 helps hair follicles resist radiation by stopping hair growth cycles.

research FGF20 Secreted From Dermal Papilla Cells Regulate the Proliferation and Differentiation of Hair Follicle Stem Cells in Fine‐Wool Sheep

3 citations , December 2024 in “Journal of Animal Physiology and Animal Nutrition”

FGF20 is essential for hair follicle stem cell growth and development in fine-wool sheep.

research A cDNA encoding the human type I hair keratin hHa1

20 citations , October 1995 in “Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression”

hHb1, hHb3, and hHb6 mRNAs start expressing at the same time in hair follicles.

research Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

638 citations , October 1997 in “Nature”

research The Insulin-like Growth Factor 1 Receptor Is Expressed by Epithelial Cells with Proliferative Potential in Human Epidermis and Skin Appendages: Correlation of Increased Expression with Epidermal Hyperplasia

128 citations , March 1996 in “Journal of Investigative Dermatology”

Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice

research Fibroblast Growth Factors Stimulate Hair Growth throughβ-Catenin and Shh Expression in C57BL/6 Mice

64 citations , January 2015 in “BioMed Research International”

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation

321 citations , January 2012 in “Cell stem cell”

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

research Faculty Opinions recommendation of GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells.

January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

GDNF helps grow hair and heal skin wounds by acting on specific stem cells.

research Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons.

5 citations , March 1993 in “The Journal of Cell Biology”

A soluble factor in developing mouse whisker pads boosts nerve growth factor mRNA production.

research Expression of bioactive recombinant human fibroblast growth factor 9 in oil bodies of Arabidopsis thaliana

16 citations , August 2015 in “Protein Expression and Purification”

Scientists successfully made a human growth factor in a plant, which could help with hair growth and bone development.

research 127 NDRG1 regulates proliferation of endothelial cells of infantile hemangioma

April 2018 in “Journal of Investigative Dermatology”

NDRG1 protein helps infantile hemangioma, a common infant tumor, to grow, and its mismanagement by FOXO1 protein plays a big role in causing the tumor.