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Promotion of Anagen, Increased Hair Density, and Reduction of Hair Fall in a Clinical Setting Following Identification of FGF5-Inhibiting Compounds via a Novel 2-Stage Process

research Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process

27 citations , February 2017 in “Clinical, Cosmetic and Investigational Dermatology”

New compounds were found to help increase hair growth and decrease hair loss.

research miR‐203a‐3p promotes loureirin A‐induced hair follicle stem cells differentiation by targeting Smad1

12 citations , June 2020 in “The anatomical record”

miR-203a-3p helps hair follicle stem cells become specialized by targeting Smad1.

research Decision letter: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells

July 2017

IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.

research Keratinocyte integrin α3β1 induces expression of the macrophage stimulating factor, CSF-1, through a YAP/TEAD-dependent mechanism.

8 citations , February 2024 in “Matrix Biology”

research A Hair Growth-Enhancing Component of Hydrolysate of Human Placenta: In vitro and In vivo Assessments

1 citations , January 2015 in “Journal of clinical and investigative dermatology”

IGF-1 from human placenta helps hair grow.

research Nuclear Factor I-C Regulates TGF-β-dependent Hair Follicle Cycling*

25 citations , August 2010 in “Journal of Biological Chemistry”

Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.

research Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep

June 2024 in “Cells”

Editing the FGF5 gene in sheep increases fine wool growth.

research 020 Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo

1 citations , October 2021 in “Journal of Investigative Dermatology”

research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells

396 citations , May 2011 in “Cell stem cell”

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

research VEGF induces proliferation of human hair follicle dermal papilla cells through VEGFR-2-mediated activation of ERK

120 citations , May 2012 in “Experimental Cell Research”

VEGF promotes hair follicle cell growth through the VEGFR-2/ERK pathway.

research Abstracts from the ASA 40thAnnual Meeting

April 2015 in “Andrology”

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

research Review of Women with Vision: The Presentation Sisters of South Dakota, 1880-1985

January 1990

Knocking out the FGF5 gene in sheep increased wool production and hair-follicle density.

In Vitro Expansion of Human Mesenchymal Stem Cells and Hepatocytes Using Purified Platelet-Derived Growth Factors: A Potential Therapeutic Modality for Liver Fibrosis

research In vitro expansion of human mesenchymal stem cells and hepatocytes using purified platelet derived growth factors, a potential therapeutic modality for liver fibrosis

April 2023 in “Egyptian journal of Immunology”

10% hPL is best for growing mesenchymal stem cells, while 10% FBS is best for hepatocytes.

Effects of the Anti-Androgen Finasteride on 5α-Reduction of Androgens in the Presence of Progesterone in Human Gingival Fibroblasts: Modulatory Actions of the Alkaline Phosphatase Inhibitor Levamisole

research Effects of the anti-androgen finasteride on 5α-reduction of androgens in the presence of progesterone in human gingival fibroblasts: modulatory actions of the alkaline phosphatase inhibitor levamisole

9 citations , August 2000 in “Journal of Periodontal Research”

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Therapeutic Effect of Exosomes Derived from Hepatocyte-Growth-Factor-Overexpressing Adipose Mesenchymal Stem Cells on Liver Injury

research Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury

8 citations , October 2023 in “Folia Histochemica et Cytobiologica”

Exosomes from modified stem cells may help treat liver injury.

research Androgen Effects in Mammals

7 citations , January 2003 in “Elsevier eBooks”

Testosterone is crucial for development, growth, and various body functions in mammals.

research Self-assembling peptide hydrogel scaffolds support stem cell-based hair follicle regeneration

38 citations , June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine”

Peptide hydrogel scaffolds help grow new hair follicles using stem cells.

research Desmogleins: Hair perspective

4 citations , January 2013 in “International Journal of Trichology”

Desmogleins are crucial for hair structure and growth.

research Cocktail Cell‐Reprogrammed Hydrogel Microspheres Achieving Scarless Hair Follicle Regeneration

January 2024 in “Advanced Science”

New microspheres help heal skin wounds and regrow hair without scarring.

research Engineered Exosomes Co-Delivering EGF and FGF Ameliorate Androgenetic Alopecia in a Mouse Model

February 2026 in “International Journal of Nanomedicine”

Engineered exosomes with EGF and FGF improved hair growth in mice with hair loss.

research Characterization of hairless (Hr) and FGF5genes provides insights into the molecular basis of hair loss in cetaceans

50 citations , February 2013 in “BMC evolutionary biology”

Cetaceans lost hair due to changes in the Hr and FGF5 genes.

research Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

145 citations , November 2018 in “Nature Communications”

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

research Hair follicle regeneration from human pluripotent stem cells

January 2017 in “Journal of clinical & experimental dermatology research”

Scientists have found a way to create hair follicles from human stem cells, which could potentially be used to treat hair loss.

research Author response: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells

October 2017

IL-1 and IL-7 help activate cells that boost hair follicle stem cell growth, aiding wound healing.

Stem Cell Factor/c-Kit Signaling in Normal and Androgenetic Alopecia Hair Follicles

research Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles

39 citations , January 2008 in “Journal of Endocrinology”

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

research Recent progress in hair follicle stem cell markers and their regulatory roles

13 citations , February 2024 in “World Journal of Stem Cells”

New markers help understand and use hair follicle stem cells for regeneration.

Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor-β (TGF-β)/Mesenchymal Stem Cells (MSCs) Balance: A Complex Partnership in Skin Rejuvenation

research Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor - β (TGF - β)/Mesenchymal Stem Cells (MSCs) Balance: A Complicated Partnership in Skin Rejuvenation

1 citations , January 2019 in “Journal of Embryology & Stem Cell Research”

MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.

research Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration

3 citations , September 2021 in “Journal of Clinical Medicine”

Epidermal signaling helps regenerate fingertip tissue.

research The role of SFRP1 in human dermal papilla cell growth and its potential molecular mechanisms as a target in regenerative therapy

December 2024 in “Regenerative Therapy”

Inhibiting SFRP1 may help treat hair loss.

research Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model

3 citations , September 2024 in “Journal of Microbiology and Biotechnology”

Human placenta extract reduces inflammation and symptoms in atopic dermatitis.

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