research Hair regeneration using microneedle-assisted human basic fibroblast growth factor
Microneedle-assisted therapy with human basic fibroblast growth factor significantly regrew hair in patients with hair loss.
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690-720 / 1000+ results research Expression of HIF in fibroblasts and its biological effects on hair follicles
HIF-1α in fibroblasts boosts hair growth and health.
research [Expression of oleosin-rhFGF9 fusion protein in Carthamus tinctorius and determination of hair regeneration and wound repair potential in mice].
The transgenic safflower oil with oleosin-rhFGF9 improved hair growth and wound healing in mice.
research β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED]
The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.
research Timely Wound Healing Is Dependent on Endothelial but Not on Hair Follicle Stem Cell Toll-Like Receptor 2 Signaling
Endothelial TLR2 is crucial for timely wound healing, but HFSC TLR2 is not needed.
research Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing
A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
research Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo
Growth hormone is important for regulating human hair growth.
research Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability
Compound 6 is a promising candidate for better wound healing.
research Epidermal Notch signalling: differentiation, cancer and adhesion
Notch signalling helps skin cells differentiate and prevents tumors.
research Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research A Mutation in the Serum and Glucocorticoid-Inducible Kinase-Like Kinase (Sgkl) Gene is Associated with Defective Hair Growth in Mice
A mutation in the Sgkl gene causes defective hair growth in mice.
research Folate receptor β performs an immune checkpoint function in activated macrophages
Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
research Melanocortins in fibroblast biology – current update and future perspective for dermatology
α-MSH may help treat skin inflammation and fibrosis.
research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model
IGF2BP3 and other m6A-related genes are linked to keloid formation and could be potential treatment targets.
research Regulation of Semaphorin3A in the process of cutaneous wound healing
Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
research Abstracts
Ablative fractional laser treatment nearly matches the gene reduction effects of topical vismodegib in skin cancer.
research A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells
Aging-related changes in hair follicle stem cells can be partially reversed with a specific treatment.
research 866 Senescent fibroblasts secretome promote tumoural initiation of normal human keratinocytes through cellular activation, enhanced migration and ECM remodelling
Senescent fibroblasts can help start tumors in normal skin cells.
research Expression of melanocortin receptors on cutaneous fibroblastic cells – collagen and beyond
MC-1R in skin cells may influence inflammation and collagen production.
research Pharmacological Application of Growth Factors: Basic and Clinical
Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.
research 1422 Uncoupling desmosomal cadherin adhesion activates quiescent hair follicle stem cells and orchestrates self-organized regeneration through outside-in signaling
Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
research Editors' Picks
Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
research Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis
CXCR2 in skin cells promotes tumor growth.
research Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape
Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.
research Glypican-1, -4 and 6 Participate in the Hair Follicle Stem Cell Differentiation via Specific Interactions with BMP2R, Fz7 and Patched 1
research 1381 Investigating the role of Mef2c in hair follicle cycling
MEF2C is crucial for normal hair cycle progression.
research Epidermal growth factor receptor inhibitors and hair
research EXPRESSION OF CONCERN: Dermal papilla cell‐secreted biglycan regulates hair follicle phase transit and regeneration by activating Wnt/β‐catenin
Biglycan helps regulate hair growth and regeneration.
research [The effect of cgVEGF164 on the growth of murine hair follicles].
cgVEGF164 boosts hair follicle growth in mice.
research Formulation and Application of a Human Insulin-Like Growth Factor 1-Loaded Transfersomal System to Enhance Skin Wound Healing in Diabetic Rat Models
The system improved diabetic wound healing in rats.