94 citations
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
29 citations
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June 2017 in “Journal of Inherited Metabolic Disease” High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
35 citations
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January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
46 citations
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August 2006 in “PubMed” A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.
1 citations
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January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Increased PHGDH expression causes early melanin buildup in hair follicles.
8 citations
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January 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Growth hormone is important for regulating human hair growth.
109 citations
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November 2011 in “Nature Neuroscience” January 2026 in “Animal Genetics” A genetic variant in the GJB6 gene likely caused the Labrador's paw pad condition.
33 citations
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May 2016 in “Translational andrology and urology” Laser hair removal before genital surgery can prevent complications and improve patient satisfaction.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created a detailed map of gene activity in different parts of human hair follicles.
18 citations
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April 1998 in “MIT Press eBooks” DMG-Na may improve blood flow and help hair growth without side effects.
January 2017 in “British journal of dermatology/British journal of dermatology, Supplement”
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
4 citations
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January 1992 in “Clinical Oncology” Some cancer treatments can cause abnormal fine hair growth.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” Digital microscopy can help diagnose hirsutism by measuring hair growth.
January 2008 in “Memorial University Research Repository (Memorial University)” Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
January 2011 in “Therapeutic research” Patients were generally dissatisfied with over-the-counter hair growth products but wanted to consult doctors for hair loss treatment.
112 citations
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January 2013 in “Experimental dermatology” Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
2 citations
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September 2007 in “International Journal of Impotence Research” Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
January 2025 in “Indian Journal of Unani Medicine” Wet cupping may improve hair health in androgenetic alopecia without side effects.
24 citations
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May 2019 in “PLOS genetics” Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
December 2013 in “Praxis medica” Using both DLQI and Skindex-16 together gives a better understanding of quality of life in skin disease patients.
137 citations
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September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
April 2018 in “Journal of Investigative Dermatology”
Shh and Dhh affect skin development and can cause tumors, while Ihh does not.
82 citations
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July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
1 citations
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June 2025 in “International Journal of Molecular Sciences” Hirsutism in GCC countries is influenced by genetics, obesity, and lifestyle, with cultural stigma delaying treatment, highlighting the need for tailored health strategies.
July 2024 in “Journal of Investigative Dermatology” Human hair follicles have their own thyroid hormone system.