research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
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research Clobetasol propionate 0.05% under occlusion in the treatment of alopecia totalis/universalis
Clobetasol propionate ointment can help some people with total hair loss regrow hair.
research Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men – short version
Use minoxidil for hair loss treatment; assess results after 6 months.
research Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells
Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.
research Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women
Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Melasma, a photoaging disorder
Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
research Epidemiology and burden of alopecia areata: a systematic review
Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.
research K ATP Channels and Cardiovascular Disease
K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
research Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function
Hair follicle stem cells can help repair spinal cord injuries and improve walking.
research Lupus erythematosus: systemic and cutaneous manifestations
Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
research Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis
The vitamin D receptor is essential for normal hair growth, even without its usual binding.
research Trichothiodystrophy: Review of sulfur-deficient brittle hair syndromes and association with the ectodermal dysplasias
research Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
Wounded skin cells can revert to stem cells and help heal.
research Laser Hair Removal: A Review
In-office laser hair removal works well long-term, especially Nd:YAG for darker skin, but home devices need more testing.
research Human keratin hydrogels support fibroblast attachment and proliferation in vitro
research Comma hairs: A dermatoscopic marker for tinea capitis
Comma hairs are a specific sign of tinea capitis when viewed with videodermatoscopy.
research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Vitamin D receptor is essential for normal keratinocyte stem cell function
Vitamin D receptor is crucial for normal hair growth and preventing hair loss.
research Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata
Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.
research Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.
LGD1069 effectively prevents breast tumors in mice without toxicity.
research Generalized Pustular Psoriasis
Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research The comparative histopathology of male-pattern baldness and senescent baldness
The understanding of male-pattern baldness remains unclear.
research Psychosomatic Concepts in Dermatology
Mental and social factors greatly affect skin conditions and doctors find it hard to deal with these aspects.
research Tactile innervation densities across the whole body
Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
Cannabinoids may help treat various skin conditions.