research Melasma, a photoaging disorder
Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
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research Epidemiology and burden of alopecia areata: a systematic review
Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.
research K ATP Channels and Cardiovascular Disease
K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
research Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function
Hair follicle stem cells can help repair spinal cord injuries and improve walking.
research Lupus erythematosus: systemic and cutaneous manifestations
Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
research Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis
The vitamin D receptor is essential for normal hair growth, even without its usual binding.
research Telogen effluvium
Telogen effluvium is a common type of hair loss that can resolve on its own or become chronic, with treatment depending on early diagnosis.
research Trichothiodystrophy: Review of sulfur-deficient brittle hair syndromes and association with the ectodermal dysplasias
research Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
Wounded skin cells can revert to stem cells and help heal.
research Laser Hair Removal: A Review
In-office laser hair removal works well long-term, especially Nd:YAG for darker skin, but home devices need more testing.
research Human keratin hydrogels support fibroblast attachment and proliferation in vitro
research Comma hairs: A dermatoscopic marker for tinea capitis
Comma hairs are a specific sign of tinea capitis when viewed with videodermatoscopy.
research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Vitamin D receptor is essential for normal keratinocyte stem cell function
Vitamin D receptor is crucial for normal hair growth and preventing hair loss.
research Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata
Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.
research Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.
LGD1069 effectively prevents breast tumors in mice without toxicity.
research ANDROGEN METABOLISM AS IT AFFECTS HAIR GROWTH IN ANDROGENETIC ALOPECIA
Too much androgen can cause hair loss; finasteride may help.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research The comparative histopathology of male-pattern baldness and senescent baldness
The understanding of male-pattern baldness remains unclear.
research Psychosomatic Concepts in Dermatology
Mental and social factors greatly affect skin conditions and doctors find it hard to deal with these aspects.
research Tactile innervation densities across the whole body
Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
Cannabinoids may help treat various skin conditions.
research Pathophysiological mechanisms implicated in postpartum depression
Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
research Foxc1 reinforces quiescence in self-renewing hair follicle stem cells
Foxc1 helps keep hair follicle stem cells inactive, preventing hair loss.
research Dissecting the Heterogeneity of Skin Gene Expression Patterns in Systemic Sclerosis
Systemic sclerosis skin shows varied gene patterns, suggesting potential for personalized treatment.
research Targeting to the hair follicles: Current status and potential
Hair follicles are promising targets for delivering drugs effectively.
research Evaluation of hypoglycemic and anti-hyperglycemic potential of Tridax procumbens (Linn.)
Tridax procumbens significantly lowers blood sugar in diabetic rats.
research A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men
New 5% minoxidil foam effectively promotes hair growth and is safe for use.
research Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.