31 citations
,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
Human hair follicle stem cells improved memory and brain health in rats.
170 citations
,
January 2010 in “animal” Hair follicle growth and fiber production in animals are influenced by chemical signals, proteins, pigmentation, genetics, and nutrients.
134 citations
,
July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.
April 2018 in “Journal of Investigative Dermatology” Key signals for hair follicle formation were identified.
31 citations
,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
6 citations
,
January 2013 in “Journal of Clinical and Diagnostic Research” AMH levels are higher in women with PCOS and can indicate the number of small follicles in their ovaries.
37 citations
,
December 2001 in “Journal of Investigative Dermatology” Leptin may play a role in hair growth and hair follicle health.
10 citations
,
December 2011 in “Cell Transplantation” Researchers successfully grew human hair follicle cells that could potentially lead to new hair loss treatments.
29 citations
,
January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
33 citations
,
March 2015 in “Experimental Dermatology” LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
April 2016 in “British Journal of Dermatology” Eyelashes are important for looks and eye protection, and more people are treating sparse eyelashes; more research is needed to understand eyelash biology and improve treatments.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
45 citations
,
October 2008 in “Cytokine & Growth Factor Reviews” Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
5 citations
,
June 2022 in “Biophysical Journal” TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.
October 2025 in “F1000Research” Postmenopausal women with excess male hormones may have ovarian tumors, and surgery usually cures them.
53 citations
,
October 2003 in “Developmental Biology” Too much Sonic Hedgehog protein stops hair growth in embryos.
27 citations
,
October 1998 in “Differentiation” Basonuclin helps identify and track hair follicle development and cycling in mice.
56 citations
,
July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
May 2026 in “Journal of Proteomics”
2 citations
,
November 2025 in “Journal of Ovarian Research” Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.
4 citations
,
August 2021 in “Theriogenology” Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.
378 citations
,
November 2011 in “Human reproduction update” Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
8 citations
,
January 1998 in “Journal of Investigative Dermatology” Topical estrogen treatments did not change hair growth in certain mouse strains, questioning previous findings on their role in hair growth control.
45 citations
,
May 2022 in “Biomedicines” Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
A stable sheep ovarian cell line was created for studying reproduction and hormones.
28 citations
,
August 2003 in “Steroids” Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
1 citations
,
December 2017 in “Acta biomedica scientifica” Women of reproductive age with polycystic ovary syndrome often experience hair loss.
7 citations
,
March 2005 in “Journal of dermatological science” Apoptosis helps shape hair growth and prepares the skin for hair to emerge.