270 citations
,
April 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.
71 citations
,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
61 citations
,
June 2016 in “Clinical Medicine” PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.
51 citations
,
October 2002 in “European journal of endocrinology” Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
50 citations
,
December 2008 in “Clinical Endocrinology” Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.
46 citations
,
June 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
39 citations
,
March 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
35 citations
,
March 2011 in “International Journal of Dermatology” No true link between AGA and insulin resistance, but coexistence may worsen AGA.
29 citations
,
March 2011 in “The Journal of Nutritional Biochemistry” Eating isoflavone can help mice grow hair by increasing a growth factor.
29 citations
,
January 2011 in “Journal of Obstetrics and Gynaecology” Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
28 citations
,
October 2013 in “Journal of The American Academy of Dermatology” Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.
27 citations
,
February 2014 in “Experimental Dermatology” IGF-1 affects hair loss and could be a potential treatment.
19 citations
,
November 2012 in “Journal of Dermatological Treatment” Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
19 citations
,
March 2007 in “Journal of diabetes science and technology” Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.
18 citations
,
August 2012 in “Cutaneous and Ocular Toxicology” People with alopecia areata have higher insulin resistance.
15 citations
,
October 2014 in “Hormone Molecular Biology and Clinical Investigation” Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
14 citations
,
January 2018 in “Endocrinology and Metabolism” Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.
10 citations
,
January 2020 in “Advances in Dermatology and Allergology” Lower ghrelin levels and certain gene variations may increase acne risk.
8 citations
,
January 2019 in “Annals of Dermatology” Bilobetin may help reduce acne by decreasing sebum production.
8 citations
,
November 2012 in “Journal of Endocrinological Investigation” Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.
6 citations
,
April 2022 in “Cellular and Molecular Life Sciences” Angio PRP speeds up skin wound healing and reduces inflammation.
6 citations
,
April 2016 in “Journal of the Formosan Medical Association” Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.
4 citations
,
June 2018 in “PLOS ONE” Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.
4 citations
,
January 2013 in “PubMed” Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
3 citations
,
August 2015 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” Married women with type 2 diabetes had a surprisingly low infertility rate, suggesting type 2 diabetes and PCOS may be different conditions.
2 citations
,
March 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
2 citations
,
January 2016 in “Journal of Steroids & Hormonal Science” Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.
March 2026 in “Current Research in Diabetes & Obesity Journal” Skin conditions can signal diabetes and insulin resistance.
December 2024 in “The New Indian Journal of OBGYN” Larger ovaries in women with PCOS may indicate higher insulin resistance.
January 2024 in “Archives of Endocrinology and Metabolism” A new gene mutation causes insulin resistance in a girl and her mother.