research Liver Cirrhosis and Circadian Rhythm
Taking high doses of fluconazole for a long time can cause reversible hair loss.
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390-420 / 1000+ results research Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
High levels of ornithine decarboxylase can cause tumors in mouse skin.
research Studies of the components of an oral contraceptive agent in albino rats. I. Estrogenic component
High doses of ethynylestradiol in rats caused growth issues, organ changes, and some tumors, but didn't increase overall tumor rates.
research Chronic toxicity of 3,4,3′,4′-tetrachlorobiphenyl in the marmoset monkey (Callithrix jacchus)
High doses of TCB cause severe health issues in marmoset monkeys.
research Acute And Sub Chronic Toxicity Of Tridax Procumbens In Experimental Animals
High doses of Tridax procumbens extract can be toxic, affecting liver and kidneys.
research Effect of Rosemary Extract on Some Internal Organs of Young Male Albino Rats: A Histological Study
High doses of rosemary extract can harm developing offspring and should be avoided during pregnancy and lactation.
research Vitamins
High doses of certain vitamins can cause serious side effects and health risks.
research Finasteride Reduces Total Cholesterol in LDLR-Deficient Mice
High doses of finasteride lower cholesterol and body weight in certain mice.
research Female pattern hair loss
Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.
research ETP026 A case of alopecia areata associated with low dosage VPA treatment
Low dose valproic acid treatment caused hair loss in a young patient.
research THE EFFECTS OF RADIOACTIVE RADIATION ON PLANTS
Radiation affects plant growth differently, with high doses being harmful, but some lower doses can increase yield.
research Effects of isotretinoin on the hair cycle
Isotretinoin at a low dose for three months does not significantly affect hair growth.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
Finasteride causes abnormal growth in male mice cells at high doses.
research Dosimetry for synchrotron x-ray microbeam radiation therapy
Microbeam radiation therapy's dose distribution changes with depth.
research Androgen Dependence of Hirsutism, Acne, and Alopecia in Women
Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
research Retinoids for Chemoprophylaxis of Nonmelanoma Skin Cancer
Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.
research Co-secretion of testosterone and cortisol by a functional adrenocortical oncocytoma
A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
research Finasteride: Middle-Age Cure-All for Alopecia and Benign Prostatic Hyperplasia?
Finasteride reduces prostate cancer risk but may increase high-grade cancer cases.
research Hormesis and medicine
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research Viable SARS-CoV-2 shedding under remdesivir and dexamethasone treatment
Infectious virus was not found after the third remdesivir dose, suggesting early end of isolation is possible.
research Cyproterone Acetate: A Genotoxic Carcinogen?
Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
research Melatonin-Mediated Circadian Rhythm Signaling Exhibits Bidirectional Regulatory Effects on the State of Hair Follicle Stem Cells
Melatonin can help or hinder hair growth depending on the dose.
research Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta)
Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.
research Antianaphylactic activity of alcoholic extract ofEclipta alba
Alcoholic extract of Eclipta alba may help treat allergies and is safe at high doses.
research Finasteride for prostatic disease: an updated and comprehensive review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research Utilisation of gonadotrophin-releasing hormone (GnRH) analogue to differentiate ovarian from adrenal hyperandrogenism in postmenopausal women
GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.
research Acute Toxicity Evaluation of Ficus Platyphylla Methanolic Leaf Extract on Wistar Rats
Ficus platyphylla leaf extract is likely safe in high doses, with minor temporary side effects.
research Acute Toxicity Evaluation of Ficus Platyphylla Methanolic Leaf Extract on Wistar Rats
Ficus platyphylla leaf extract is likely safe in high doses for rats.
research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
research Embryo‐Fetal Developmental Toxicity and Toxicokinetics Studies of YWS1903 , a Novel Potassium‐Competitive Acid Blocker, in Pregnant Rats
YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.