269 citations
,
May 2002 in “Hormones and Behavior” Lowering 3α,5α-THP in the hippocampus increases anxiety and depression in proestrous rats.
83 citations
,
July 2004 in “Pharmacology Biochemistry and Behavior” Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
82 citations
,
July 2011 in “Journal of Neuroscience” Ethanol boosts brain steroid production by activating NMDA receptors, affecting memory formation.
61 citations
,
April 2018 in “Frontiers in endocrinology” Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.
32 citations
,
October 2015 in “Frontiers in Cellular Neuroscience” DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.
32 citations
,
May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
22 citations
,
October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
19 citations
,
November 2015 in “Radiation Oncology” Hippocampus sparing whole brain radiation therapy prevents hair loss and preserves cognitive function.
18 citations
,
January 2013 in “Psychoneuroendocrinology” Neonatal neurosteroid levels affect adult brain function and behavior.
14 citations
,
May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
14 citations
,
March 2017 in “Brain research” Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.
11 citations
,
October 2010 in “Behavioural Brain Research” Early neurosteroid changes can alter adult brain function and behavior.
10 citations
,
May 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.
10 citations
,
February 2017 in “European journal of neuroscience/EJN. European journal of neuroscience” The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.
7 citations
,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
5 citations
,
February 2019 in “Neuroscience letters” Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
4 citations
,
January 2025 in “International Journal of Molecular Sciences” Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
3 citations
,
June 2025 in “Journal of Cellular and Molecular Medicine” CuATSM speeds up wound healing and reduces scarring.
3 citations
,
January 2022 in “Journal of neuroendocrinology” Sex hormones affect brain cells differently in males and females.
2 citations
,
January 2025 in “动物学研究” YAP1 helps fat cell formation by influencing the Hippo pathway.
2 citations
,
August 2011 in “Revista Medica De Chile” A postmenopausal woman's high testosterone levels and symptoms improved after removing a tumor from her ovary.
May 2026 in “Journal of Tissue Engineering” A new treatment using cell secretions can regrow hair better than minoxidil.
January 2026 in “Frontiers in Cellular Neuroscience” Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.
August 2025 in “Cermin Dunia Kedokteran” Low blood albumin often signals disease-related stress, not poor nutrition, and requires treating the cause and possibly supplementing albumin.
May 2025 in “Psychopharmacology” Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.
February 2025 in “FASEB BioAdvances” Verteporfin reduces growth and stem cell traits in rat hair follicle cells by blocking the Hippo pathway.
Finasteride may cause memory problems by damaging the hippocampus.
March 2024 in “Residência Pediátrica” An infant developed excessive hair growth after a bone marrow transplant and cyclosporine treatment.
January 2024 in “International journal of molecular sciences” A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.
August 2023 in “Scientific reports” Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.