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May 2009 in “Hippocampus” Progesterone helps adult male mice grow more neurons and improves memory.
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April 2019 in “Journal of Investigative Dermatology” Merkel cell carcinoma is most likely to recur within two years of diagnosis, and factors like immune suppression, being over 75, and male sex increase this risk.
April 2023 in “Journal of Investigative Dermatology” Changing YBX1 protein activity affects skin stem cell function and aging.
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August 1999 in “Nature Genetics”
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May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.
Lhx2 helps retinal cells respond to signals for eye development.
January 2008 in “Memorial University Research Repository (Memorial University)” Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.
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July 2014 in “Molecular Biology Reports”
Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.
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November 2017 in “General and comparative endocrinology” BMP2 and BMPR-IA may stop hair growth while Noggin may encourage it in yak skin.
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January 2015 in “Biochemical Society Transactions” The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.
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November 2019 in “The FASEB Journal” A mutation in the MAP2 gene causes reduced hair follicle density, leading to hairlessness.
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February 1993 in “Journal of Biological Chemistry” KAP6 genes are conserved across species and active in hair follicles.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
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October 2023 in “PROTOPLASMA”
August 2016 in “Journal of Investigative Dermatology” Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
April 2026 in “Apollo (University of Cambridge)”
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupting YAP signaling in skin cells leads to scar-free healing directed by specific cell signals.
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September 2014 in “SpringerPlus” Sheep have a unique gene, KAP8-2, that humans don't have, which may affect wool properties.
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Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
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March 1995 in “Differentiation” A rabbit gene important for hair development was identified and detailed.