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Complete Defect in PA-PLA1α Secretion Function Leading to Autosomal Recessive Woolly Hair and Hypotrichosis: Insights from a Novel Compound Heterozygous LIPH Variant Study in a Chinese Pedigree

research Complete defect in PA-PLA1α secretion function leading to autosomal recessive woolly hair and hypotrichosis: insights from a novel compound heterozygous LIPH variant study in a Chinese pedigree

May 2025 in “Frontiers in Genetics”

A new genetic variant in the LIPH gene causes hair growth issues in a Chinese patient.

research Decision letter: ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas

October 2015

ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.

research Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice

7 citations , August 2008 in “Immunogenetics”

A gene mutation in mice causes increased mast cells and disorganized hair follicles in their skin.

TYK2 Inhibition with Deucravacitinib Improves Clinical Outcomes and Resolves Interferon-Driven Inflammation in Lichen Planopilaris

research TYK2 Inhibition with Deucravacitinib Improves Clinical Outcomes and Resolves Interferon-Driven Inflammation in Lichen Planopilaris

March 2026

Deucravacitinib improves symptoms and reduces inflammation in Lichen Planopilaris.

research Role of ASLNC168501 in regulating hair follicle stem cell activity via the AR/miR-128-3p/IGF-1 pathway

January 2026 in “Stem Cell Research & Therapy”

ASLNC168501 can help treat hair loss by restoring hair follicle stem cell function.

research Hair Cycle-Specific Immunolocalization of Retinoic Acid Synthesizing Enzymes Aldh1a2 and Aldh1a3 Indicate Complex Regulation

29 citations , July 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

The enzymes Aldh1a2 and Aldh1a3 are involved in making retinoic acid in hair follicles and have different roles in hair growth.

Clinical Snippets: Research Findings in Dermatology

research Clinical Snippets

January 2016 in “Experimental Dermatology”

New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.

research 0843 N6-methyladenosine RNA modification promotes keratinocyte proliferation and cutaneous wound repair through regulation of MTOR stability

1 citations , July 2025 in “Journal of Investigative Dermatology”

Increasing m6A levels can improve skin cell growth and wound healing.

research 583 Hair cycle regulation by a mitochondrially localized protein: Is MPZL3 a central component of the elusive hair cycle clock?

April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

MPZL3 protein is important for controlling hair growth cycles.

research A Homozygous Frameshift Mutation in theHOXC13Gene Underlies Pure Hair and Nail Ectodermal Dysplasia in a Syrian Family

30 citations , January 2013 in “Human Mutation”

A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.

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