research Repositioning Old Drugs for New Battles: The Expanding Role of Drug Repurposing in Cancer, Inflammation, and Metabolic Disease.
Drug repurposing can create safer, cheaper treatments by finding new uses for existing drugs.
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research Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing
Deep skin fibroblasts help recruit immune cells for better wound healing.
research Methionine Dependence of Hair Maintenance in C57BL/6 Mice
Methionine is essential for hair maintenance in C57BL/6 mice.
research LncRNA-miRNA-mRNA regulatory networks in skin aging and therapeutic potentials
ceRNA networks offer potential treatments for skin aging and wound healing.
research The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Defining the transcriptional signature of esophageal-to-skin lineage conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
research SNP variation in male pattern hair loss in Russians with different dihydrotestosterone levels
Certain gene variations increase male hair loss risk, influenced by hormone levels.
research Biotechs target stagnant baldness market
New drug shows promise for better hair growth in baldness treatment.
research Dynamic Wnt5a expression in murine hair follicle cycle and its inhibitory effects on follicular
Wnt5a may slow down hair growth in mice.
research Formation of the cornified envelope
The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
research Alopecia areata: a comprehensive review of clinical, immunologic, and genetic perspectives
Alopecia Areata is an autoimmune disease causing hair loss, with no cure yet, but research may lead to new treatments.
research Late Onset Systemic Lupus Erythematosus - Clinical and Autoantibody Profile and its Comparison with Young Onset Systemic Lupus Erythematosus
Late onset SLE has different symptoms and antibody profiles compared to young onset SLE.
research Gut microbiome, metabolome and alopecia areata
The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.
research Maternal androgen excess inhibits fetal cardiomyocytes proliferation through RB-mediated cell cycle arrest and induces cardiac hypertrophy in adulthood
Excess maternal androgens can cause heart problems in offspring.
research New insights into inflammatory memory of epidermal stem cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
research Systemic Circulating Leptin – Aiding New Dimension of Immune-Related Skin Carcinogenesis and Lipid Metabolism
High leptin levels may promote skin cancer and inflammation, suggesting potential for leptin-targeted therapies.
research Identification of the key proteins associated with different hair types in sheep and goats
Different proteins are linked to the varying thickness of sheep and goat hair types.
research Triple-Negative Sjogren’s Syndrome and Recurrent Pneumothorax: An Uncommon Presentation of Autoimmune Disease
Recurrent pneumothorax can occur in Sjogren's syndrome, even without common markers.
research Hair cortisol in polycystic ovary syndrome
Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
research Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli
KGF-1 135 is a stable and effective alternative for treating oral mucositis.
research Role of the Wnt signaling pathway in keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
research Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53
Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.
research Immune-Mediated Skin Reactions Induced by Recombinant Antibodies and Other TNF-Alpha Inhibitors
TNF-alpha inhibitors can cause various immune-related skin issues.
research Low level of maternal biotin intake changes the expression of biotin transporter in dams and fetuses in mice
Low biotin intake during pregnancy can affect biotin transport in mothers and fetuses.
research Bexxar, iodine I 131 tositumomab, Effective in Long Term Follow-up of Non-Hodgkin's Lymphoma
Bexxar is highly effective as a first treatment for non-Hodgkin's lymphoma, with most patients alive and many in remission after eight years.
research LUPUS ERYTHEMATOSUS AND THE SKIN
Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.
research A symphony of signals: the intricate role of lncRNAs in dermatological disorders
lncRNAs are important for understanding and treating skin diseases.
research Sexually dimorphic sail feathers in the Mandarin duck as a model for lifelong developmental modulation
Mandarin duck sail feathers change with seasons due to hormones and genetic regulation.
research Causality of Aging Hallmarks
Lengthening telomeres may reverse aging and extend lifespan.