116 citations
,
December 2013 in “European journal of endocrinology” Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.
60 citations
,
February 2010 in “Gynecological Endocrinology” Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
21 citations
,
December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
18 citations
,
July 2019 in “Clinical Endocrinology” Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.
14 citations
,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
3 citations
,
January 2012 in “Hanyang Medical Reviews” The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
February 2024 in “Journal of Education, Health and Sport” Different treatments for PCOS should be tailored to the individual, including lifestyle changes and various medications.
Low-dose glucocorticoid treatment improves pregnancy and birth rates in women with nonclassical 21-hydroxylase deficiency.
January 2020 in “Proyecto de investigación:” Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.
November 2004 in “John Wiley & Sons, Ltd eBooks” Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
7 citations
,
December 2014 in “Gynecological Endocrinology” LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
October 2010 in “Reproductive Biomedicine Online” Women with pituitary adenomas often have reproductive issues, like irregular periods and trouble getting pregnant, but not always breast milk production without pregnancy.
947 citations
,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
200 citations
,
October 2009 in “European journal of endocrinology” Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
47 citations
,
June 2015 in “Medicines” Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.
December 2023 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” Both photobiomodulation and low-frequency treatments effectively reduce body measurements.
January 2015 in “Indian Journal of Medical Biochemistry” Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
July 2024 in “International Journal of Chemical and Biological Sciences” Glypican-4 may help indicate insulin sensitivity and lipid issues in women with PCOS.
March 2024 in “International journal of life-sciences scientific research/SSR Institute of International Journal of Life Sciences” PCOS has many symptoms, with high androgen levels being the most common.
October 2025 in “Nepal Journal of Dermatology Venereology & Leprology” PCOS is the main cause of hirsutism, often linked to insulin resistance.
13 citations
,
December 2020 in “BMJ Open Diabetes Research & Care” Changes in SHBG levels don't predict diabetes risk reduction.
20 citations
,
June 2020 in “Journal of Advanced Research” High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.
February 2026 in “International Journal of Molecular Sciences” Targeting mitochondria can improve skin healing and rejuvenation.
3 citations
,
March 2017 in “Iraqi Journal of Pharmaceutical Sciences” Silymarin and metformin together most improved hormone levels and ovulation in women with PCOS.
February 2022 in “Mediators of Inflammation” Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
41 citations
,
June 2023 in “Antioxidants” Pomegranate has health benefits and new methods are improving its use in supplements.
16 citations
,
January 2023 in “Gynecological Endocrinology” Liver damage in PCOS is linked to iron overload and cell death due to the miR-761-hepcidin/GPX4 pathway.
8 citations
,
March 2022 in “International Journal of Endocrinology” Combining spironolactone with metformin reduces insulin resistance in PCOS better than either drug alone.
3 citations
,
December 2016 in “PubMed” Menstrual abnormalities in PCOS women may not greatly affect their metabolic and hormonal profile.