January 2021 in “Revista Dermatológica Centro Uraga” Endocrinological evaluation is crucial for properly diagnosing and treating acne.
22 citations
,
March 2018 in “American Journal of Clinical Dermatology” New acne treatments show promise as alternatives to traditional therapies.
21 citations
,
January 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Acne is an important sign of androgen excess disorders in women.
20 citations
,
June 2010 in “International Journal of Dermatology” Women with mild acne are more likely to have polycystic ovary syndrome (PCOS) than those without acne.
13 citations
,
September 2016 in “Acta Médica Portuguesa” Many adults in Porto have acne, but few know or treat it.
12 citations
,
May 2017 in “Journal of Dermatological Treatment” Adult acne severity is influenced by stress, skin sensitivity, makeup, stopping oral contraceptives, and requires female-specific treatment guidelines.
11 citations
,
May 2000 in “International Journal of Dermatology” Taking a small dose of prednisone before menstruation can almost completely prevent premenstrual acne with few side effects.
10 citations
,
January 2016 in “Dermatologic Clinics” Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.
9 citations
,
April 2021 in “Expert opinion on pharmacotherapy” Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
2 citations
,
July 2022 in “Cutis” Diet may influence acne development.
1 citations
,
August 2024 in “Journal of Cutaneous and Aesthetic Surgery” 65% TCA improves acne scars more but has more side effects than 50% GA.
June 2026 in “International Journal of Innovative Technologies in Social Science” Acne vulgaris affects up to 90% of people, with increasing cases in those over 25. Traditional treatments like isotretinoin and antibiotics have significant side effects and limitations. Clascoterone, a new topical antiandrogen cream, blocks androgen receptors, reducing sebaceous gland activity and inflammation with fewer systemic side effects. It is effective for both acne and androgen-related alopecia, approved for patients aged 12 and older, and poses a low risk of feminization and gynecomastia in males. However, caution is advised during pregnancy. Clascoterone represents a significant advancement in acne treatment, offering efficacy and safety with minimal side effects.
June 2026 in “Quality in Sport” Treating hirsutism and acne in women with PCOS needs a personalized approach using oral contraceptives, antiandrogens, and sometimes metformin.
March 2026 in “International Journal of Homoeopathic Sciences” An integrative homeopathic approach may help manage acne, but more research is needed.
Spironolactone may be a better acne treatment for adult women than antibiotics.
232 citations
,
June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
78 citations
,
June 2021 in “Dermatology and Therapy” Future acne treatments should aggressively target inflammation to prevent scarring.
68 citations
,
May 2011 in “European Journal of Dermatology” Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
65 citations
,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
43 citations
,
January 2007 in “Gynecological Endocrinology” Finasteride improves acne and hair loss in women with normal testosterone.
30 citations
,
March 2001 in “Environmental Health Perspectives” Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
28 citations
,
January 2003 in “Urologic oncology” Suppressing certain hormones might help prevent prostate cancer.
27 citations
,
June 2017 in “International Journal of Dermatology” The study suggests that acne keloidalis nuchae is linked to conditions like pseudofolliculitis barbae, scalp infections, metabolic syndrome, and is more common in males with an average onset age of 25.4 years.
22 citations
,
August 2013 in “International journal of gynaecology and obstetrics” Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.
21 citations
,
February 2017 in “International Journal of Women's Dermatology” Hormonal therapies help treat female hair loss, but results are slow and vary.
21 citations
,
October 2009 in “Dermatology” Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.
19 citations
,
April 2019 in “Journal of the European Academy of Dermatology and Venereology” Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.
19 citations
,
November 2012 in “Journal of Dermatological Treatment” Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
15 citations
,
April 2022 in “Biointerface Research in Applied Chemistry” Medicinal plants may be an effective alternative for treating acne.
15 citations
,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.