62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
42 citations
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April 2009 in “Human Genetics” A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.
37 citations
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November 1995 in “Journal of Investigative Dermatology” Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
33 citations
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January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
24 citations
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March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
19 citations
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January 2001 in “Dermatology + psychosomatics” The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.
18 citations
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June 1988 in “Culture, medicine and psychiatry” The perception of excessive hair growth in women as abnormal is more influenced by cultural norms than by medical reasons.
14 citations
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November 1982 in “British Journal of Dermatology” Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
11 citations
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September 2020 in “Steroids” A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.
11 citations
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January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
11 citations
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March 2014 in “Journal of The European Academy of Dermatology and Venereology” Hair loss gene linked to prostate issues.
9 citations
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January 1966 in “Economic botany” Plant-based ingredients in hair care are being replaced by synthetic alternatives.
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
6 citations
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December 2013 in “Journal of Dermatological Science” Women with alopecia may have a higher chance of getting thyroid cancer.
March 2024 in “Brazilian Journal of Veterinary Pathology” The dog likely has a canine alopecia X-like disorder.
March 2024 in “Research Square (Research Square)” Sex steroids affect the MafB gene differently in male and female hamsters.
January 2024 in “Brazilian journal of veterinary pathology” The dog likely has a condition similar to Canine alopecia X.
May 2023 in “Animal Reproduction Update” High levels of cortisol in hair show long-term stress which can lower fertility in animals.
September 2016 in “Princeton University Press eBooks” The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
November 1983 in “American Biology Teacher” Pattern baldness is likely caused by a dominant gene influenced by testosterone levels, making it more common in men.
7 citations
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January 2019 in “Postepy Dermatologii I Alergologii” Certain gene variations might be linked to severe acne in women but not in men.
March 2023 in “Revista Chilena de Urología” Post-finasteride syndrome can cause sexual and systemic side effects, and patients should be informed about these risks.
1540 citations
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October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
363 citations
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May 2006 in “Current Opinion in Psychiatry” Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.
284 citations
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February 2008 in “Pediatrics” Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
269 citations
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May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
169 citations
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June 2010 in “Molecular & cellular proteomics” Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.
122 citations
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July 1990 in “Teratology” Finasteride exposure in pregnancy causes genital abnormalities in male rats.
102 citations
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July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
70 citations
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November 1984 in “Cell & tissue research/Cell and tissue research” Vitamin D3 affects cell differentiation in specific skin areas.