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Grizzly and black bears have different stress and hormone responses to salmon availability, influenced by nutrition and social competition.

Trastuzumab deruxtecan is effective for advanced breast cancer but has side effects like nausea and fatigue.

150 kHz electromagnetic radiation might help improve PCOS in rats.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Men have more severe COVID-19 outcomes than women.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Hair loss in men is common, treatable, but not curable.

The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The study improved understanding of gene roles in cashmere goat hair growth, aiding future cashmere production.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.