research Skin manifestations of hyperandrogenism: an update
Targeting androgen receptors in the skin is the most effective treatment for hyperandrogenism-related skin issues.
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research Non-competitive androgen receptor inhibition in vitro and in vivo
Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
research Skin Aging and Menopause
Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
research Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer
Hair loss gene linked to prostate issues.
research Sexual function in women with androgen excess disorders: classic forms of congenital adrenal hyperplasia and polycystic ovary syndrome
Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.
research Mouse models with a disrupted PTHrP gene or a disrupted PTH gene (PTH−/− mice)
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
research Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine
The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
research Vitamin D Receptor: New Assignments for an Already Busy Receptor
The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
research Is COVID-19 Gender-sensitive?
Men have more severe COVID-19 outcomes than women.
research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females
Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
research Estrogens and the skin
Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
research Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor β Gene Are Associated with Androgen Levels in Women1
Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.
research Epidermal stem cells and skin tissue engineering in hair follicle regeneration
Hair follicle regeneration needs special conditions and young cells.
research Androgenetic alopecia in men and women
Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
research Skin ageing
After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.
research Menopause and aging, quality of life and sexuality
Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
research Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research Prescribing testosterone and DHEA: The role of androgens in women
Testosterone and DHEA can benefit women's health but must be prescribed carefully due to potential risks.
research Effects of finasteride, a 5 alpha-reductase inhibitor, on circulating androgens and gonadotropin secretion in hirsute women.
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
research Comparative Analysis of Machine Learning Algorithms in Diagnosis of Polycystic Ovarian Syndrome
The Random Forest algorithm was the most accurate at diagnosing Polycystic Ovarian Syndrome.
research Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Mechanism of Salutary Effects of Finasteride on Post-traumatic Immune/Inflammatory Response
Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.
research Androgenetic alopecia in a postmenopausal woman as a result of ovarian hyperthecosis
Hair loss in postmenopausal woman caused by ovarian issue.
research Environmental Influences on the Hair Follicle
Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research Alopecia and hirsutism*
The document says that hair loss in women is often due to androgenic alopecia, similar to male baldness, and that hirsutism is treated with hormonal and cosmetic methods.
research Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach
Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
research Menopause
The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.