13 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Four drugs were found that could potentially treat COVID-19 by inhibiting the virus in lab tests.
133 citations
,
May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
19 citations
,
August 2024 in “Cell Host & Microbe”
192 citations
,
March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
179 citations
,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
63 citations
,
September 2009 in “Regenerative Medicine” Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
40 citations
,
December 2015 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
8 citations
,
January 2011 in “Experimental and Therapeutic Medicine” Stromal cells in melanoma promote tumor growth and spread.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
182 citations
,
June 2017 in “Biomaterials” Special fiber materials boost the healing properties of certain stem cells.
163 citations
,
March 2012 in “BMC biology” Stem cell niches support, regulate, and coordinate stem cell functions.
2 citations
,
January 2016 in “Springer eBooks” Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
188 citations
,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
83 citations
,
June 2018 in “Frontiers in immunology” Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
50 citations
,
December 2013 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
48 citations
,
February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
48 citations
,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
27 citations
,
April 2018 in “Scientific Reports” Psoriasis patients' immune response to a hair protein depends on their specific gene type.
23 citations
,
January 2021 in “Scientific Reports” Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
23 citations
,
May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
22 citations
,
March 2017 in “Scientific reports” Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.
20 citations
,
November 2019 in “Current Opinion in Systems Biology” The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
15 citations
,
August 2006 in “Journal of Cutaneous Pathology” HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
14 citations
,
October 2019 in “Journal of Cellular Physiology” Micrografts promote hair growth in androgenetic alopecia treatment.
14 citations
,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
14 citations
,
October 2012 in “Clinics in Plastic Surgery” Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.
7 citations
,
March 2019 in “Frontiers in Cellular and Infection Microbiology” Understanding how our bodies interact with mosquito-borne viruses is crucial because there are few treatments and vaccines.
6 citations
,
January 2016 in “Dermatology Review” Stem cells show promise for treating skin conditions and aiding healing.
5 citations
,
August 2020 in “Stem Cell Research & Therapy” Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.