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To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease

research To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease

23 citations , April 2016 in “American Journal of Pathology”

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

research SKPing a Hurdle: Sox2 and Adult Dermal Stem Cells

11 citations , December 2009 in “Cell stem cell”

Sox2-expressing cells can help grow hair and heal skin.

research Impaired skin and hair follicle development in Runx2 deficient mice

34 citations , January 2008 in “Developmental Biology”

research RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene

February 2025 in “Biomolecules”

RORA boosts autophagy in hair follicle stem cells, potentially aiding hair growth.

research Mutant Cx43 in Skin Differentiation and Disease

January 2011

Mutant Cx43 causes slower wound healing and hair growth issues in ODDD.

Variable Expressivity of Syndromic BMP4-Related Eye, Brain, and Digital Anomalies: A Review of the Literature and Description of Three New Cases

research Variable expressivity of syndromic BMP4-related eye, brain, and digital anomalies: A review of the literature and description of three new cases

7 citations , May 2019 in “European Journal of Human Genetics”

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome

1 citations , May 2022 in “International journal of molecular sciences”

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

MLO-Mediated Ca2+ Influx Regulates Root Hair Tip Growth in Arabidopsis

research MLO‐mediated Ca²⁺ influx regulates root hair tip growth in Arabidopsis

July 2025 in “New Phytologist”

MLO proteins help regulate calcium and ROS levels, promoting root hair growth in Arabidopsis.

WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

research WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

197 citations , June 2009 in “American journal of human genetics”

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

research The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal

1 citations , October 2022 in “Biomedicines”

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

research Conversion of C57Bl/6 mice from a tumor promotion-resistant to a -sensitive phenotype by enhanced ornithine decarboxylase expression

31 citations , September 1999 in “Molecular Carcinogenesis”

Increased ornithine decarboxylase makes normally tumor-resistant mice more sensitive to tumors.

research The Mammalian Hairless Protein as a DNA Binding Phosphoprotein

6 citations , June 2016 in “Journal of cellular biochemistry”

The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.

Whole-Transcriptome Analysis Reveals the Profiles and Roles of Coding and Non-Coding RNAs During Hair Follicle Cycling in Rex Rabbits

research Whole-transcriptome analysis reveals the profiles and roles of coding and non-coding RNAs during hair follicle cycling in Rex rabbits

January 2025 in “BMC Genomics”

Key genes and RNA networks regulate hair growth and follicle density in Rex rabbits.

research Regulation of a hair follicle keratin intermediate filament gene promoter

39 citations , December 1998 in “Journal of Cell Science”

The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.

CRABP1 Enhances Proliferation of Dermal Papilla Cells in Hu Sheep via Wnt/β-Catenin Pathway

research CRABP1 Enhances the Proliferation of the Dermal Papilla Cells of Hu Sheep through the Wnt/β-catenin Pathway

September 2024 in “Genes”

CRABP1 boosts hair cell growth in Hu sheep by affecting key genes.

research Identification and profiling of microRNA between back and belly Skin in Rex rabbits (Oryctolagus cuniculus)

1 citations , June 2018 in “World rabbit science”

Different miRNAs in Rex rabbit skin affect cell processes and hair growth.

research USING THE FROG EPIDERMIS TO UNCOVER DESMOSOME FUNCTION AND REGULATION IN THE DEVELOPING EMBRYO

January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)”

Desmosomes are crucial for skin and heart development, and JNK may help regulate them.

research Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin.

94 citations , October 1994 in “The Journal of Cell Biology”

Too much keratin 16 in mice skin causes abnormal skin thickening and structure.

research Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages

July 2025 in “Pharmaceutics”

Recombinant Human Annexin A5 may help treat localized scleroderma by reducing skin thickening and inflammation.

research Epidermal Differentiation Enhances CRABP II Expression in Human Skin

21 citations , December 1994 in “Journal of Investigative Dermatology”

research Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways

45 citations , August 2009 in “American Journal Of Pathology”

Noggin promotes skin tumors by activating certain cell signaling pathways.

research Concerted gene duplications in the two keratin gene families

53 citations , May 1988 in “Journal of Molecular Evolution”

research Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice

7 citations , August 2008 in “Immunogenetics”

A gene mutation in mice causes increased mast cells and disorganized hair follicles in their skin.

research Hair-Specific Keratins: Characterization and Expression of a Mouse Type I Keratin Gene

27 citations , November 1991 in “Journal of Investigative Dermatology”

research Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice

19 citations , January 2013 in “International journal of medical sciences”

Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.

research Deletion of an Enhancer in FGF5 is Associated With Ectopic Expression in Goat Hair Follicles and the Cashmere Growth Phenotype

1 citations , October 2020 in “Research Square (Research Square)”

A genetic variant in goats is linked to cashmere growth.

research Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes

226 citations , August 2006 in “Molecular and Cellular Biology”

EGF signaling affects gene expression in skin cells, influencing hair growth and potentially cancer.

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