research CS12192 Reverses Alopecia Areata by Selectively Targeting JAK3/JAK1/TBK1.
CS12192 effectively treats alopecia areata with better safety than current options.
Search
for
Sort by
Research
900-930 / 1000+ results 
research A Comparison of the Efficacy, Relapse Rate and Side Effects among Three Modalities of Systemic Corticosteroid Therapy for Alopecia Areata
Intramuscular triamcinolone and pulse therapy with oral predonine are effective for alopecia areata with manageable side effects, but better relapse prevention is needed.
research Children’s hair cortisol as a biomarker of stress at school: a follow-up study
Children with lower inhibitory control experience more stress when starting third grade.
research Treatment of hirsutism with the pure antiandrogen flutamide
Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
research The Role of 11-Oxygenated Androgens and Endocrine Disruptors in Androgen Excess Disorders in Women
PCOS involves high 11-oxygenated androgens and BPA may worsen it, while IH is not inflammatory.
research Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgen
Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
research 700 Tyrosine kinase 2 inhibition rescues hair follicles from IL-12–mediated immune privilege collapse and reverses the induction of human alopecia areata in a humanized mouse model
Inhibiting TYK2 can restore hair growth in alopecia areata.
research 898 Homeostatic activation of epidermal HSD11b1 affects skin innervation and non-histaminergic itch
HSD11b1 affects skin nerves and increases non-histaminergic itch.
research Insulin resistance, nitric oxide, and fibrinogen levels in white hirsute women: Defining a new paradigm based on translational research
White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
research Optimizing psychological interventions for trichotillomania (hair-pulling disorder): an update on current empirical status
Cognitive-behavioral therapy is the best treatment for hair-pulling disorder, and combining it with other therapies could improve results.
research Treatment of idiopathic facial hirsutism with medroxyprogesterone acetate iontophoresis
Medroxyprogesterone acetate iontophoresis safely and effectively reduces facial hair growth in women.
research Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege
Hair follicle cells help protect against immune attacks by regulating T-cell activity.
research 1432 IL-9/IL-9R signaling as a novel regulator of human hair follicle growth and immune privilege
IL-9/IL-9R signaling can negatively affect human hair growth and may be a target for treating hair loss conditions.
research Sequential estrogen-progestin addition to gonadotropin-releasing hormone agonist suppression for the chronic treatment of ovarian hyperandrogenism: a pilot study.
The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
research Acne-associated syndromes: models for better understanding of acne pathogenesis
Studying acne-related syndromes helps us understand acne causes and can lead to new treatments.
research Five key criticism about theory of marginal utility
HPE may help treat osteoarthritis by promoting cartilage regeneration.
research An Approach to the Patient With Hirsutism
Most women with hirsutism have normal hormone levels and can be treated with cosmetic methods; obesity and PCOS are common causes, and treatments depend on the underlying issue.
research 294 Extensive alopecia areata is reversed by IL-12/23p40 cytokine antagonism
Blocking certain proteins can significantly regrow hair in severe alopecia areata.
research 130 Deciphering the role of the hexosamine pathway in skin homeostasis
The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.
research Principles of Hair Cycle Control
Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
research Prevalence of Depression and Anxiety in Women with Polycystic Ovary Syndrome (PCOS) and Associated Factors: A Cross-Sectional Study
Women with PCOS, especially with hirsutism, should be screened for depression and anxiety.
research Hidradenitis Suppurativa: From Physiopathologies to Targeted Therapeutics
Hidradenitis suppurativa is a chronic skin disorder linked to genetics, lifestyle, and immune issues, treatable with medication and sometimes surgery.
research HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy
HDAC6 helps keep ovarian follicles dormant, extending female fertility.
research Efficacy of low-dose GnRH analogue (Buserelin) in the treatment of hirsutism
Low-dose Buserelin effectively reduces hirsutism with minimal side effects.
research Somatostatin Expression in Human Hair Follicles and Its Potential Role in Immune Privilege
Somatostatin may help protect hair follicles from immune attacks.
research Witnessed trauma exposure induces fear in mice through a reduction in endogenous neurosteroid synthesis
Reduced neurosteroid production increases fear in mice, suggesting potential PTSD treatments.
research Faculty Opinions recommendation of Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial.
DHEA therapy improved pubic hair growth and psychological well-being in young females with adrenal insufficiency.
research Spatial transcriptome reveals disturbance of peri-infundibular immune infiltration in androgenetic alopecia
Hair loss in male pattern baldness is linked to changes in immune cell behavior around hair follicles.
research Correlation of immunological variables of interleukin-17 and heat shock protein-70 in ethnic women with polycystic ovary syndrome
A 3-month treatment improved PCOS symptoms and reduced certain immune proteins.
research Hidradenitis Suppurativa: From Physiopathologies to Targeted Therapeutics
Hidradenitis suppurativa is a chronic skin disorder linked to genetics, lifestyle, and immune issues, treatable with medications and surgery.