research Hairless Up‐Regulates Tgf‐β2 Expression via Down‐Regulation of miR‐31 in the Skin of “Hairpoor” (HrHp) Mice
HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.
Search
for
Sort by
Research
660-690 / 1000+ resultsresearch Inactivity of Hidradenitis Suppurativa After Renal Transplantation
A kidney transplant and immunosuppressive treatment stopped the skin disease in a patient.
research 0054 Treg-targeted therapies restrain disease in a murine model of alopecia areata
Enhancing Tregs can protect against alopecia areata.
research [Hirsutism].
Hirsutism, excessive male-pattern hair in women, can be caused by high androgens or skin sensitivity, diagnosed by testosterone levels, and treated with hair removal and hormone therapy.
research Expression of Hypothalamic–Pituitary–Thyroid Axis RelatedGenes in the Human Skin
Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
research Clinical, Biochemical and Molecular Characteristics of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency
21-hydroxylase deficiency causes hormone imbalances leading to various symptoms, and diagnosis involves clinical and genetic tests.
research What’s new in hidradenitis suppurativa?
The document concludes that awareness and understanding of hidradenitis suppurativa are increasing, but effective treatments are still needed.
research Measurement and comparison of various androgen levels in women with severe acne, hirsutism, and androgenic alopecia
Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
research Interventions for hirsutism (excluding laser and photoepilation therapy alone)
Some medicines can reduce excessive hair growth in women, but more research is needed to compare treatments and consider side effects.
research Hairless down-regulates expression of Msx2 and its related target genes in hair follicles
Hairless protein reduces Msx2 gene activity, affecting hair follicle development.
research Keep quiet—how stress regulates hair follicle stem cells
Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.
research Clinical and Investigative Study of Hirsutism
Idiopathic hirsutism is the most common cause, followed by PCOS, and insulin resistance should be checked in patients with acanthosis nigricans.
research Hidradenitis suppurativa treated with finasteride
Finasteride effectively treats hidradenitis suppurativa for most patients.
research HHV-6 reactivations in immunocompetent patients with psychiatric disorders: visual hallucinations or possible interactions?
HHV-6 reactivation may be linked to psychiatric disorders and can improve with antiviral treatment.
research Hypoxia inducible factor-1a promotes trichogenic gene expression in human dermal papilla cells
A protein called HIF-1a helps control hair growth genes and could be targeted to treat hair loss.
research Antiandrogen therapy with spironolactone for the treatment of hidradenitis suppurativa
Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.
research Circulating monocytes as a marker of response to adalimumab in patients with hidradenitis suppurativa
This retrospective study of 143 patients with hidradenitis suppurativa (HS) treated with adalimumab found that baseline monocyte counts can predict treatment effectiveness. Patients with monocyte counts \(\geq\) 925/\(\mu\)l had a significantly higher risk of adalimumab ineffectiveness, with a hazard ratio of 5.87. Drug survival rates at 12 and 24 months were significantly higher in patients with lower monocyte counts, at 95.7% and 90.6%, compared to 61.5% and 52.7% in those with higher counts. The optimal monocyte count cut-off for predicting response was \(\geq\) 925/\(\mu\)l, with a specificity of 90.5% and sensitivity of 46.2%. Other factors like age, BMI, and HS severity did not significantly affect treatment outcomes.
research P-12 ACTH-INDEPENDENT CUSHING SYNDROME WITH INCONCLUSIVE ADRENAL CT SCAN RESULTS
Ketoconazole improved symptoms of ACTH-independent Cushing syndrome despite inconclusive initial scans.
research Adult Onset Isolated Hypogonadotropic Hypogonadism- a Cause of Secondary Amenorrhea
A 23-year-old woman's missed periods were caused by a rare genetic disorder treated with hormone patches.
research SAT-LB2 Elevated Testosterone Secondary to Leydig Cell Hyperplasia in Bilateral Ovaries
A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.
research SAT0631-HPR WHEN CAN I STOP MY STEROIDS? THE PATIENT PERSPECTIVE ON GLUCOCORTICOID USAGE IN ADULT INFLAMMATORY MYOPATHY
Patients need better information about the risks of long-term steroid use.
research Phenobarbital
A woman experienced unusual hair loss and skin reactions after taking phenobarbital, but her hair grew back after treatment.
research Spironolactone in combination drug therapy for unresponsive hirsutism
Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.
research The effect of the antiandrogen IIα-hydroxyprogesterone on sebum production and cholesterol concentration of sebum
The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
research Women with clinically significant hirsutism always have detectable endocrinological abnormalities
All women with significant unwanted hair growth have hormonal imbalances, often from polycystic ovary syndrome.
research [Disorder of hair growth in hyperprolactinemia].
High prolactin levels can cause skin and hair symptoms similar to those caused by hormone imbalances.
research HIRSUTISM
The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.
research Analysis of hidradenitis suppurativa–linked mutations in four genes and the effects of PSEN1-P242LfsX11 on cytokine and chemokine expression in macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research An Approach to the Patient With Hirsutism
Most women with hirsutism have normal hormone levels and can be treated with cosmetic methods; obesity and PCOS are common causes, and treatments depend on the underlying issue.
research Co‐localization of alopecia areata and lichen planopilaris in a patient receiving immunosuppressants: A rare case
A woman on immunosuppressants developed two rare scalp conditions, which improved with specific treatments.