15 citations
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January 2018 in “Biomedical Reports” Exosomes are important for skin health and could help diagnose and treat skin diseases.
June 2023 in “Medical records-international medical journal” Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.
49 citations
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March 2018 in “Toxicological sciences” Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
8 citations
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May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
2 citations
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December 2022 in “PNAS nexus” SCD-153 shows promise as an effective topical treatment for alopecia areata.
153 citations
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
98 citations
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August 2007 in “PLoS ONE” Myc changes chromatin in stem cells, causing them to leave their niche.
February 2026 in “Frontiers in Medical Technology” Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
11 citations
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March 2021 in “Journal of Bioscience and Bioengineering” Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.
480 citations
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August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
308 citations
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September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
136 citations
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May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
56 citations
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March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
51 citations
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May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
17 citations
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February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
16 citations
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August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
15 citations
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July 2013 in “Cell Reports” Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
14 citations
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November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
December 2016 in “Paleontological Journal” Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
218 citations
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January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
10 citations
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June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
November 2023 in “Linköping University medical dissertations” Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
1 citations
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February 2025 in “Scientific Reports” CD4 is crucial for maintaining skin stem cell balance and aiding wound healing.
354 citations
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February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
137 citations
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April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
91 citations
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August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.