research Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane
iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
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research Expansion of Human Dermal Papilla Cells for Clinical Applications Using Human Platelet-rich Plasma as a Substitute for Fetal Bovine Serum
Human platelet-rich plasma is better than fetal bovine serum for growing cells that help hair regrow.
research Collagen-type synthesis in human-hair papilla cells in culture
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Age‐associated decrease in GDNF and its cognate receptor GFR α‐1 protein expression in human skin
Human skin has less GDNF and its receptor with age.
research Applications of Human Pluripotent Stem Cell–Derived Skin Organoids in Dermatology
Skin organoids from stem cells can help study and treat skin issues but face some challenges.
research Hair Follicle Organoids Using Human iPSC-Derived Ectodermal Precursor Cells for Hair Regenerative Medicine
Human stem cells can help grow hair for regenerative medicine.
research Human epidermal neural crest stem cells as a source of Schwann cells
Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
research Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture
Tectoridin helps human hair cells grow and makes mouse hair longer, suggesting it could treat hair loss.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing
Reprogramming adult fibroblasts may enable scar-free healing.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerating Healing
Mimicking fetal wound environments may enable scarless healing in adults.
research OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases
OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
research Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
research Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine
Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
research The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation
Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
research Fetal Fibroblast Transplantation via Ablative Fractional Laser Irradiation Reduces Scarring
The treatment combining laser and fetal fibroblasts effectively reduces scarring.
research ZO-1 boosts the in vitro self-renewal of pre-haematopoietic stem cells from OCT4-reprogrammed human hair follicle mesenchymal stem cells through cytoskeleton remodeling
ZO-1 helps hair follicle stem cells renew better by changing their structure.
research Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic
Different skin cells produce unique materials, which can improve skin substitutes for healing.
research Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells
Engineered skin can grow chimeric hair follicles only with mouse dermal papilla cells.
research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis
Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
research Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration during Wound Healing
Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
research Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats’ Follicle Development Assessed by Whole-Transcriptome Sequencing Technology
FGF10 and non-coding RNAs are important for cashmere goat hair follicle development.
research Effects of Allium hookeri Extracts on Hair-Inductive and Anti-Oxidative Properties in Human Dermal Papilla Cells
Allium hookeri extract may help promote hair growth and protect cells from damage.
research Tissue homeostasis
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Skin fibroblast functional heterogeneity in health and disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets
Choosing the right method to separate skin layers is key for good skin cell research.
research Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming
Long-term skin biopsy cultures can produce many fibroblasts that remain functional and can be reprogrammed.
research Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods
The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
research Human dermal stem cells differentiate into functional epidermal melanocytes
Human dermal stem cells can become functional skin pigment cells.
research Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning
Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.