research Advanced therapies of skin injuries
New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
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540-570 / 1000+ results research Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin
Overexpression of COX-2 in mice skin causes abnormal skin and hair development.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane
iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Organotypic culture of outer root sheath cells from human hair follicles using a new culture device
The new device improves human hair follicle cell growth and differentiation.
research Human skin color: Origin, variation and significance
Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
research Peroxisome Proliferator–Activated Receptor-γ−Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium
PPAR-γ signaling improves mitochondrial function in hair follicles, potentially affecting hair growth and aging.
research Evaluation of clinical and trichoscopic features of androgenetic alopecia and its relation with disease severity
PFD patch helps laser tattoo removal, trichoscopy diagnoses AGA, and serum boosts SOD activity.
research A cell-based system for screening hair growth-promoting agents
Apigenin may help promote hair growth and could treat hair loss.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs
Laminin 332 is essential for normal skin cell behavior and structure.
research Induction of hair follicle neogenesis with cultured mouse dermal papilla cells in de novo regenerated skin tissues
Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
research Four murine monoclonal antibodies specific for the inner root sheath in the human hair follicle
Four antibodies were developed to help study hair follicle cell differentiation.
research Topically applied N,N-Dimethylglycine Sodium Salt Enhances Human Skin Blood Flow by Inducing Endothelial Nitric Oxide Release
Applying DMG-Na to the skin increases blood flow and may help with skin conditions.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment
SM04755 may be an effective topical treatment for psoriasis.
research Loss of epidermal PLCg1 induced sebaceous gland hyperplasia and sparse hair
Removing PLCg1 from skin cells caused thicker oil glands and less hair in mice.
research Hair cycle control by leptin as a new anagen inducer
Leptin, a hormone, is important for starting hair growth.
research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects against Malignant Progression
Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
research Ligand‐independent Regulation of the hairless Promoter by Vitamin D Receptor†
Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.
research Culture of amelanotic melanocytes derived from human fetal hair follicles
Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.
research 873 The effect of Cilostazol on hair growth: A novel therapeutic option for the treatment of hair loss
Cilostazol may help hair grow and could be a new treatment for hair loss.
research SOX2 in the Skin
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin
Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.
research Development of a novel in vitro strategy to understand the impact of shaving on skin health: combining tape strip exfoliation and human skin equivalent technology
The method effectively mimics shaving damage on skin for testing skincare products.
research 0846 Wnt signaling drives hair follicle regeneration in wounds by attenuating mechanotransduction in the epidermis
Wnt signaling helps regenerate hair follicles in wounds by reducing skin cell sensitivity to mechanical stress.