149 citations
,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
30 citations
,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
17 citations
,
December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
4 citations
,
August 2020 in “Applied Materials Today” Hydrogel microcapsules help create cells that boost hair growth.
2 citations
,
June 2022 in “Scientific reports” Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
January 2021 in “Journal of cosmetology & trichology” L-(+)-Tartaric Acid may help increase certain hair growth genes without harming cells.
300 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
16 citations
,
April 2015 in “Lasers in Surgery and Medicine” Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
2 citations
,
May 2019 in “Advances in wound care” Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
130 citations
,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
11 citations
,
March 2020 in “Cellular Signalling” XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.
June 2026 in “Frontiers in Bioengineering and Biotechnology” Hair follicle systems are being engineered to better mimic natural hair follicles for studying hair disorders and testing treatments.
December 2016 in “Paleontological Journal” Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
14 citations
,
June 2018 in “Frontiers in pharmacology” Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.
4 citations
,
June 2021 in “Basic and Clinical Neuroscience Journal” Rat hair follicle stem cells can improve nerve repair and muscle function after injury.
May 2020 in “Research Square (Research Square)” Hair follicle stem cells may help treat strokes.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
87 citations
,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
60 citations
,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
38 citations
,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
35 citations
,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
13 citations
,
October 2017 in “Bioscience, Biotechnology, and Biochemistry” Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.
10 citations
,
January 2016 in “Annals of Dermatology” 3D-cultured dermal papilla cells are better at inducing hair follicles than adipose-derived stem cells.
8 citations
,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
6 citations
,
July 2012 in “Experimental Dermatology” The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.
May 2026 in “Frontiers in Cell and Developmental Biology” Collagen networks play a key role in hair loss and follicle miniaturization.
May 2023 in “Research Square (Research Square)” Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.
Dermal stem cells help regenerate hair follicles and heal skin wounds.