8 citations
,
October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
Canine fetal hair follicle stem cells show pluripotency, with higher S100 protein expression at 40 days.
4 citations
,
April 2011 in “Stem Cell Reviews and Reports” The research helps understand how stem cells turn into hair follicle cells.
3 citations
,
September 2022 in “Frontiers in veterinary science” Melatonin affects cashmere growth in goats by influencing stem cell and certain signaling pathways.
71 citations
,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
10 citations
,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
7 citations
,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
44 citations
,
January 2015 in “Development” Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
June 2024 in “Synthetic and systems biotechnology” A fragment of human type XVII collagen shows great potential for skin health and wound healing.
May 2023 in “Experimental Dermatology” Male pattern hair loss may be linked to the developmental origins of hair follicles.
21 citations
,
June 2018 in “Current Opinion in Genetics & Development” Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
12 citations
,
April 2019 in “Nature protocols” Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.
6 citations
,
July 2019 in “Experimental Dermatology” Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.
2 citations
,
January 2022 in “Stem cell biology and regenerative medicine” The book "Hair Follicle Regeneration" discusses the potential of regenerating human hair follicles or activating dormant ones as a possible cure for baldness, and the promising role of new technologies like 3D printing in this field.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
57 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
66 citations
,
December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
9 citations
,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
17 citations
,
March 2012 in “The Journal of Pathology” In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
16 citations
,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
21 citations
,
September 2010 in “Cancer Prevention Research” Overactive signaling in hair follicles can lead to skin cancer.
February 2025 in “Theranostics” 3D bioprinting with special hydrogels can create artificial skin that heals wounds and regrows hair in mice.
156 citations
,
December 2012 in “Cell Stem Cell” TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
4 citations
,
August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science” Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.
9 citations
,
March 2018 in “Plastic and Aesthetic Research” Direct hair implantation with special pens improves hair transplant precision and effectiveness.
35 citations
,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
518 citations
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November 2014 in “Science” Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.