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research Alopecia - the search for novel agents continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Proteomic analysis of fetal skin by iTRAQ reveals molecular signals underlying Inner Mongolia Cashmere goat hair follicle initiation
The research identified proteins that change as goat hair follicles begin to form, helping to understand how cashmere grows.
research New Plant Extracts Exert Complementary Anti‐Hair Loss Properties in Human In Vitro and Ex Vivo Models
The plant extracts may help treat hair loss by promoting hair growth and reducing DHT levels.
research The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia
Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
research High-sulfur protein deficient human hair: clinical aspects and biochemical study of two unreported cases of a variant type of trichothiodystrophy
Two patients had a unique form of trichothiodystrophy with reduced high-sulfur proteins in their hair.
research In vitro hair growth‐promoting effect of Lgr5‐binding octapeptide in human primary hair cells
A synthetic octapeptide may help promote hair growth and counteract hair loss.
research In vitro Hair Growth Promoting Effects of Naringenin and Hesperetin on Human Dermal Papilla Cells and Keratinocytes
Naringenin and Hesperetin may help hair grow and protect hair cells from damage.
research Factors influencing hydrocortisone permeation into human hair follicles: Use of the skin sandwich system
Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
research Hair Biology and Care Product Ingredients from Marine Organisms
Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.
research Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth
PPAR alpha may help in hair growth and could be a target for treatment.
research Defining Hair Follicles in the Age of Stem Cell Bioengineering
The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
research The disrupted balance between hair follicles and sebaceous glands inHoxc13‐ablated rabbits
Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.
research Isolation of Multipotent Nestin-Expressing Stem Cells Derived from the Epidermis of Elderly Humans and TAT-VHL Peptide-Mediated Neuronal Differentiation of These Cells
Stem cells from elderly skin can become neurons, offering potential for brain therapy.
research Incorporation of hair follicles in 3D bioprinted models of human skin
3D bioprinting can now create skin with hair-like structures for medical use.
research Structural Transition of Trichocyte Keratin Intermediate Filaments During Development in the Hair Follicle
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Penetration profile and human cadaver skin distribution of finasteride from vesicular nanocarriers
Ethosomal carriers effectively deliver hair loss drug into skin.
research The slick hair coat locus maps to chromosome 20 in Senepol-derived cattle
The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.
research Hair follicles and their role in skin health
Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
research Introduction to JID Symposium Proceedings 52nd Annual Montagna Symposium on the Biology of Skin “Stem Cells in Skin” Held at Snowmass, Colorado, USA, June 13–17, 2003
Adult somatic stem cells could be used for future skin therapies.
research Analysis of proliferation, apoptosis and keratin expression in cultured normal and immortalized human buccal keratinocytes
SVpgC2a cells show abnormal growth and keratin changes, modeling early cancer development.
research Disease causing homozygous variants in the human hairless gene
New and known mutations in the hairless gene cause a hair loss condition called Atrichia with papular lesions.
research Collagen Hydrolysate from the Scales of Mozambique Tilapia (Oreochromis mossambicus) Improve Hair and Skin Health by Alleviating Oxidative Stress and Inflammation and Promoting Hair Growth and Extracellular Matrix Factors
Collagen from tilapia scales may improve hair and skin health by reducing stress and inflammation and encouraging hair growth.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/− Mice
Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
research Recent advances in the genetics of alopecia areata
New research has found 14 genes linked to the risk of developing alopecia areata, improving understanding and treatment options.
research Epidermal patterning and induction of different hair types during mouse embryonic development
Different body areas in mice produce different hair types due to interactions between skin layers.
research Stability of opiates in hair fibers after exposure to cosmetic treatment
Cosmetic treatments like bleaching and perming can greatly reduce opiate levels in hair, possibly leading to false-negative drug tests.