research Minoxidil increases 17β-hydroxysteroid dehydrogenase and 5α-reductase activity of cultured human dermal papilla cells from balding scalp
Minoxidil boosts enzymes that help hair growth.
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research Quantitative study of the human hair follicle in normal scalp and androgenetic alopecia
Alopecia causes smaller hair follicles and affects growth-related structures.
research Re-Evaluating Cyclosporine A as a Hair Growth–Promoting Agent in Human Scalp Hair Follicles
Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.
research Simple and rapid method to isolate and culture follicular papillae from human scalp hair follicles
Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
research Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles
Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
research Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a
Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.
research Topical cyclosporin induces hair growth in human split skin grafted onto nude mice.
Topical cyclosporin promotes hair growth.
research Restorative effect of hair follicular dermal cells on injured human hair follicles in a mouse model
Human hair follicle dermal cells can help repair damaged hair follicles.
research Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts
Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
research Topically applied thyroid hormones stimulate hair growth in organ-cultured human scalp skin
Applying thyroid hormones to the scalp can help hair grow.
research Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction
Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.
research Surgical treatment of secondary cicatricial alopecia of scalp and eyebrow
Surgery for scar-related hair loss on the scalp and eyebrow was successful in 75% of patients.
research The patch assay reconstitutes mature hair follicles by culture-expanded human cells
The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
research Impact of adipose-derived stem cells on engineering hair follicle germ-like tissue grafts for hair regenerative medicine
Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.
research Fat grafting of hairy areas of head and neck - comparison between lipofilling and nanofat grafting procedures in a cadaveric study
Nanofat grafting is better for delicate areas and combining it with lipofilling might improve hair loss treatment.
research A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair
The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.
research The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen
Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
research Stem cells from human hair follicles: first mechanical isolation for immediate autologous clinical use in androgenetic alopecia and hair loss
Stem cells from hair follicles can safely treat hair loss.
research Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia
Micrografts improve hair density and thickness without side effects.
research Regeneration of a New Hair Follicle from the Upper Half of a Human Hair Follicle in a Nude Mouse
The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.
research Safety and efficacy of hairy scalp donors in thick split-thickness skin grafting: Healing and complications at donor sites
Scalp skin is a good option for skin grafts, healing well with proper care.
research Superiority of occipital donor sites for split‐thickness skin grafting in dermatosurgery: Results of a prospective randomized controlled study
Occipital donor sites for skin grafts heal faster, hurt less, look better, and have fewer complications than femoral sites.
research Reconstruction of the Scalp, Calvarium, and Frontal Sinus
The document concludes that careful surgical methods and choosing the right materials are key for successful scalp, skull, and frontal sinus reconstruction.
research Scalp Surgery
Scalp surgery guidelines ensure best cosmetic results and fewer complications.
research Ozone interactions with human hair: Ozone uptake rates and product formation
Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.
research Quantifying whole human hair scalp fibres of varying curl: A micro‐computed tomographic study
Human hair varies in structure based on curl type, with high curl hair showing the most differences.
research Whole-Cell Bioprocessing of Human Fetal Cells for Tissue Engineering of Skin
Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.
research 3D Modelling for Solar Erythemal UV Protection Provided by Human Hair
Human hair provides more UV protection when aligned and at higher angles, but the scalp still gets UV exposure.
research Scalp and calvarial reconstruction
The conclusion is that closing scalp wounds is possible, but restoring hair without donor material is still a major challenge.