research Treatment of longstanding alopecia areata universalis of the eyebrows/facial hair with oral and topical tofacitinib
Oral and topical tofacitinib can effectively treat severe hair loss with minimal side effects.
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research The effects of topical diazoxide on hair follicular growth and physiology of the stumptailed macaque
Diazoxide applied to the skin can increase hair growth without harmful side effects.
research Protein and biologically active supplements (BAS): influence on human health and sports results
Supplements improve health, appearance, and athletic performance.
research Acute and Chronic Telogen Effluvium
Hair shedding that lasts more than 6 months may need medical tests, but often just reassurance is enough.
research Hormone und Behaarung
Hormones, especially androgens, affect hair growth and can cause hair loss or excess hair in both men and women.
research Prostaglandin D2(PGD2); prostaglandin D2 receptor (CRTH2; GPR44; CD294); prostaglandin D2 synthase (PTGDS)
Blocking a protein called prostaglandin D2 might help treat hair loss.
research Exclamation marks and other trichoscopic signs of chemotherapy-induced alopecia
Chemotherapy can cause hair changes similar to alopecia areata, which might lead to misdiagnosis.
research The Chronic Thermal Stress Model of Androgenetic Alopecia: A Unified Environmental–Vascular–Molecular Hypothesis
DHT increases scalp heat, causing hair loss.
research Gelişmekte olan insan fetüslerinin ve yetişkinlerin derisinde EZH2 ekspresyonu: karşılaştırmalı bir çalışma
EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.
research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells
Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research 801 TEC family kinase inhibitors as a novel class of therapeutics in alopecia areata
ITK inhibitors may effectively treat alopecia areata.
research CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia
CDK4/6 inhibitors can protect hair cells from chemotherapy damage.
research Discoid lupus alopecia complicated by frontal fibrosing alopecia on a background of androgenetic alopecia
Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.
research 516 Possible role of ILC1 in the pathogenesis of alopecia areata (AA)
ILC1 cells contribute to hair loss in alopecia areata.
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research 329 In vitro co-culture models of merkel cell-neurite complex in touch domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Immune privilege and alopecia areata
Restoring immune privilege in hair follicles could help treat certain types of hair loss.
research A New Humanized Mouse Model for Alopecia Areata
A new mouse model helps understand and find treatments for alopecia areata.
research 1385 Characterizing the expression of metabolic markers in alopecia areata
The research identified unique metabolic activities in immune cells associated with hair loss in Alopecia Areata.
research Clinical Snippets
New treatments for hair growth and psoriasis may be possible, and gene differences could affect baldness and the severity of skin conditions.
research Abstract 81
Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
research Congenital atrichia with papular lesions
Congenital atrichia with papular lesions causes permanent hair loss and skin bumps due to a gene mutation.
research Allergic contact dermatitis from dyes in wigs following diphencyprone treatment
Avoiding dyed wigs and clothing improved severe allergic reactions in a woman treated with diphencyprone.
research Inborn Errors of Biotin Metabolism
Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.
research Autoimmunity: Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
research SnapshotDx Quiz: August 2019
The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
research Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata
Lower MC2R expression may contribute to alopecia areata.
research How a Bird Gets Its Feathers: Insights from Chromatin Looping
Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.
research IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia
IGFBP-rP1 could be a new treatment for a common type of hair loss.