research The cell biology of human hair follicle pigmentation
We need more research on human hair follicle pigmentation, not just mouse models.
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research Human long-term deregulated circadian rhythm alters regenerative properties of skin and hair precursor cells
Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
research Failure of passive transfer of serum from patients with alopecia areata and alopecia universalis to inhibit hair growth in transplants of human scalp skin grafted on to nude mice
Serum from alopecia patients does not stop hair growth in grafted skin on mice.
research Topical cyclosporin induces hair growth in human split skin grafted onto nude mice.
Topical cyclosporin promotes hair growth.
research Exploring the Efficacy and Potential Mechanisms of Topical Periplaneta americana (L.) Extract in Treating Androgenetic Alopecia in a Mouse Model: A Systems Pharmacology and Skin Microbiome Analysis
Periplaneta americana extract promotes hair growth and is safe for treating hair loss.
research IL-17 axis is a significant driver of skin inflammation in Card14 mutant pityriasis rubra pilaris model mice
Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
research Skin Cancer: Mechanisms and Human Relevance
Skin cancer involves complex mechanisms, risk factors, and can be potentially prevented with strategies like dietary changes and certain compounds.
research Autoimmune Disease Induction in a Healthy Human Organ: A Humanized Mouse Model of Alopecia Areata
Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
research Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid
Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
research Folate bioavailability in reconstructed skin models and effects of folate in a monolayer wound healing assay. Approaches on topic application
Topical folates can penetrate skin and enhance wound healing.
research Restoration of hair growth with topical diphencyprone in mouse and rat models of alopecia areata
Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
research A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice.
CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
research Finding models for skin diseases: successes and failures
The document concludes that while finding animal models for the skin disease Hidradenitis suppurativa is challenging, certain mouse mutations may provide useful insights for research and drug testing.
research Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools
Mouse models help study genetic skin diseases.
research The influence of CD26+ and CD26− fibroblasts on the regeneration of human dermo-epidermal skin substitutes
CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
research 237 Unveiling Skin Cancers Pathophysiology via the Modeling of Xeroderma Pigmentosum Disease Modeling Using CRISPR-Cas9 Technology
Blocking the JAK/STAT pathway may help reduce skin sensitivity in Xeroderma pigmentosum.
research 176 Characterising Neurotransmitter Signalling in Human Skin and Hair Follicles
Skin and hair cells release serotonin and histamine naturally, which could help improve skin health.
research Merkel cell polyomavirus infection and persistence modelled in skin organoids
Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
research 585 Effects of a LED light therapy mask on an ex vivo skin model and clinical signs of aging
The LED light therapy mask improved skin elasticity and reduced signs of aging in a test and in women aged 40-60.
research Analogs of human genetic skin disease in domesticated animals
Some domesticated animals have the same genetic skin diseases as humans, which can help doctors understand human genetic mutations.
research 132 Design of an in vitro skin 3D model mimicking a disruption of the barrier function
Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
research Inherited disorders of the skin in human and mouse: from development to differentiation.
Research on skin disorders in humans and mice has improved understanding of hair and skin development.
research Keratin gene mutations in disorders of human skin and its appendages
Keratin gene mutations cause various skin and hair disorders, but new research offers hope for future treatments.
research The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration
400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
research 487 Exploring ribosomal RNA modifications and corresponding snoRNAs in human skin cell senescence
Understanding snoRNA regulation may help slow skin aging.
research Silymarin enhanced fibroblast proliferation and tissue regeneration in full thickness skin wounds in rat models; a stereological study
Silymarin improved wound healing and skin regeneration in rats.
research Characterization of factors that determine lentiviral vector tropism in skin tissue using an ex vivo model
Lentiviral vector effectiveness in skin is influenced by external factors, not receptor availability.
research Interleukin-1 and Keratinocyte Growth Factor/Fibroblast Growth Factor-7 Gene Expression in Skin Experimental Irritant Contact Dermatitis Mouse Model Treated with Aqueous Extract of Trachyspermum copticum (L.) Link Seeds
Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.
research Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita
Loss of Ten1 in mice causes telomere shortening and symptoms similar to human dyskeratosis congenita.
research Topical Products for Human Hair Regeneration: A Comparative Study on an Animal Model
Minoxidil was the most effective treatment for hair regrowth in rats compared to Aminexil or Kerium.