74 citations
,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
41 citations
,
September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
26 citations
,
January 2016 in “Annals of Dermatology” Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.
17 citations
,
December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
4 citations
,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists can now create skin with hair by reprogramming cells in wounds.
6 citations
,
March 2019 in “Medical science monitor basic research/Medical science monitor. Basic research” VEGFR-2 is active in hair follicles, sebaceous glands, sweat glands, and skin on the human scalp.
150 citations
,
August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
24 citations
,
June 2012 in “BMC Research Notes” The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
1 citations
,
January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
June 2017 in “Acta Scientiae Veterinariae” A cat with a rare pancreatic tumor and diabetes died despite treatment, showing similar symptoms to a human condition.
96 citations
,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
30 citations
,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
62 citations
,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
105 citations
,
January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
11 citations
,
October 2017 in “International Journal of Molecular Sciences” A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
10 citations
,
June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
4 citations
,
January 2017 in “Biological & pharmaceutical bulletin” Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
25 citations
,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
22 citations
,
October 2012 in “Cell Transplantation” Cells treated with Wnt-10b can grow hair after being transplanted into mice.
13 citations
,
March 2013 in “International Journal of Cosmetic Science” AcSDKP may help prevent skin and hair aging and promote their growth.
3 citations
,
August 2023 in “World Journal of Biology and Biotechnology” The human microbiome is vital for health and can help treat diseases.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
March 2016 in “Institutional Repositories DataBase (IRDB)” Collagen peptides may promote hair growth by activating certain genes in the skin.
829 citations
,
May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
94 citations
,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
44 citations
,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
19 citations
,
November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.