Hairlessness in mammals is caused by combined changes in genes and regulatory regions.
23 citations
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December 1977 in “Virchows Archiv B Cell Pathology” 18 citations
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February 1992 in “Molecular Biology Reports” A specific type II hair keratin was identified and found in hair cortex and tongue cells.
49 citations
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September 2008 in “International journal of pharmaceutics” Artificial sebum L closely mimics human sebum for drug delivery research.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles can be used to create heart muscle cells.
43 citations
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August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
252 citations
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January 1991 in “Electron Microscopy Reviews”
22 citations
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November 2011 in “Journal of Analytical Toxicology” Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
10 citations
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January 2012 in “Journal of Biological Macromolecules” Keratin film can effectively replace human hair for testing hair damage.
1 citations
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January 1985 in “Protides of the biological fluids” Injecting monocyto-angiotropin into hare skin increases hair growth by forming new blood vessels.
140 citations
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August 2010 in “Pigment Cell & Melanoma Research” We know a lot about mouse hair color, but not much about human hair color differences.
19 citations
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December 2006 in “Journal of Structural Biology” Type I and Type II keratin chains can form heterodimers despite sequence differences.
52 citations
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October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
1 citations
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September 2019 in “Journal of Investigative Dermatology” Human hair matrix cells and dermal papilla fibroblasts can form early hair follicle structures but don't produce hair shafts yet.
January 2023 in “Advances in pharmacology and clinical trials” Human hair is a significant sample for various tests in clinical, nutritional, archaeological, and forensic studies.
25 citations
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March 2004 in “Regulatory Toxicology and Pharmacology” Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
January 2003 in “Jiepouxue zazhi” HHK can help restore skin structure.
37 citations
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January 1993 in “Journal of Investigative Dermatology”
April 2023 in “Journal of Investigative Dermatology” Human TMEM2 does not break down hyaluronan but helps control its metabolism.
February 2024 in “Scientific Reports” The wolves suspected of man-eating in the 1880s likely ate very little human flesh and mostly consumed a diet similar to herbivores and omnivores.
25 citations
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October 1984 in “Journal of Clinical Investigation” The model using human skin on mice helps study human sebaceous glands.
1 citations
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August 2024 in “Journal of Morphology” Mammary glands evolved from hair organs in Monodelphis domestica.
66 citations
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August 2001 in “Experimental Dermatology” Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.
2 citations
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August 2019 in “Electronics and Communications in Japan” The device mimics human hair follicles and detects tiny forces and moments with high sensitivity.
February 1985 in “PubMed”
November 2022 in “Journal of Investigative Dermatology” Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
12 citations
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May 2016 in “Experimental Dermatology” A new skin model from hair follicles is a safer, simpler alternative for skin tests.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
1 citations
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November 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” Male and female human hairs have different microscopic structures that can help in forensic analysis.
425 citations
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June 2020 in “Nature” Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.