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December 2024 in “EXPERIMENTAL ANIMALS” B6J mice live longer before 24 months, but B6N mice live longer after; both strains show weight gain, increased food and water intake, and health issues as they age.
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May 2002 in “PubMed” LGD1069 effectively prevents breast tumors in mice without toxicity.
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March 2009 in “Journal of Investigative Dermatology” Proteomic analysis can identify genetic differences in mouse hair, helping understand hair defects and variations.
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January 1985 in “Protides of the biological fluids” Injecting monocyto-angiotropin into hare skin increases hair growth by forming new blood vessels.
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October 2003 in “Developmental Biology” Too much Sonic Hedgehog protein stops hair growth in embryos.
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November 2014 in “Cytotechnology” 8 citations
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December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
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September 2020 in “Advanced Biology” Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.
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January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
April 2023 in “Journal of Investigative Dermatology” A new image-based method improves accuracy in measuring hair loss in mice.
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June 2022 in “Developmental cell” Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
October 2024 in “Frontiers in Immunology” Pertussis toxin may contribute to hair loss in alopecia areata.
The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.
Alopecia areata is an autoimmune disease that targets hair follicles.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.
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March 2005 in “Journal of Molecular Medicine” Certain mice without specific receptors or mast cells don't lose hair from stress.
January 2005 in “Chinese Journal of Veterinary” Hairless mice lose hair by 3-4 weeks, develop thicker, folded skin, and show pigmentation differences.
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February 2008 in “The American journal of pathology” Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
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January 2024 in “Microorganisms” Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
May 2009 in “OPAL (Open@LaTrobe) (La Trobe University)” Suppressing the HGPS mutation may improve symptoms and suggest reversibility.
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November 2017 in “PLoS ONE” Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.
January 2008 in “Medical Entomology and Zoology”
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.
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June 2003 in “Applied immunohistochemistry & molecular morphology” Combining cell conditioning with mild protease digestion effectively shows versican mRNA in mouse skin sections.
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September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
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January 1987 in “Carcinogenesis” TCDD changes skin cell growth and keratin production in mice.
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June 2003 in “PubMed” Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
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May 2019 in “International Journal of Molecular Sciences” Tranexamic acid turns white hair brown in certain mice by affecting specific proteins.
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April 1979 in “Journal of Ultrastructure Research” February 2025 in “Buletin Veteriner Udayana”